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2015 CPT changes for DRUG ASSAYS- THERAPEUTIC DRUG ASSAY


Therapeutic Drug Assays are performed to monitor known, prescribed medication. The results are reported in quantitative values. Two codes have been added to the Therapeutic Drug Assays.

CPT Code               Code Description
80163                       Digoxin; free
80165                       Valproic acid (dipropylacetic acid); free

Digoxin; free is being added to compliment the current code for Digoxin, which does not provide information regarding free, total and bound digoxin in the body.

Valproic acid (dipropylacetic acid); free, does the same as the new digoxin code, it provides the measurement of the “free” valproic acid in the body whereas currently the testing doesn’t separate free from total or bound.

Performance of the testing procedure is not limited to a particular method; therefore, these codes are intended to be used for any quantitative method. If the testing of the parent drug also identifies a metabolite of the parent drug, the metabolite is included in the parent drug CPT code and is not separately reported.

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