Home » 2015 new CPT code for SURGICAL PATHOLOGY( MORPHOMETRIC ANALYSIS – IN SITU HYBRIDIZATION)

2015 new CPT code for SURGICAL PATHOLOGY( MORPHOMETRIC ANALYSIS – IN SITU HYBRIDIZATION)

88377 cpt code

These new clarified guidelines will require pathologist/laboratories to clearly document when a multiplex/cocktail stained probe procedure has been performed for morphometric analysis by in situ hybridization.

Unit of service for morphometric analysis by in situ hybridization is per specimen, per separate single probe stain procedure.

Use code:
• CPT 88367 or CPT 88368 (semi/quantitative–depending on manual versus computer assisted) for the first single probe stain procedure

CPT 88373 or CPT 88369 for semi/quantitative—depending on manual or computer assisted for each additional single probe stain procedure.

For multiplex staining procedures: Use CPT 88374 or CPT 88377 (semi/quantitative—depending on manual versus computer assisted) when multiple antibodies on a probe by a single staining procedure.

The terms “single probe stain procedure” and “multiplex probe stain procedure” will play a vital part in the units of service as well as the code(s) that is selected. Using the term single probe stain procedure indicates that the same probe that may contain multiple different antibodies on that probe must be assigned the code associated with multiplex probe stain procedure.

It is the procedure that also determines the unit of service of that multiplex probe stain. If the probe(s) are performed in one single stain procedure, then you must consider that one unit of service for that multiplex probe.

For example, if a morphometric analysis by in situ hybridization is performed with a dual probe containing two different antibodies on that single probe, reported in semi/quantitative value…that is one unit of service of CPT 88374 or CPT 88377 (depending on semi/quantitative–manual versus computer assisted).

CPT Code: 88369 CPT Code
Code Description:
Morphometric analysis, in situ hybridization (quantitative or semi-quantitative), manual,
per specimen; each additional single probe stain procedure (List separately in addition
to code for primary procedure)
Use 88369 CPT Code in conjunction with 88368 CPT Code

CPT CODE: 88373 CPT Code
Code Description:
Morphometric analysis, in situ hybridization (quantitative or semi-quantitative), using
computer-assisted technology, per specimen; each additional single probe stain
procedure (List separately in addition to code for primary procedure)
Use 88373 CPT Code in conjunction with 88367 CPT Code

CPT CODE: 88374 CPT Code
Code Description:
Morphometric analysis, in situ hybridization (quantitative or semi-quantitative), using
computer-assisted technology, per specimen; each multiplex probe stain procedure
Do not report 88367 CPT Code, 88374 CPT Code in conjunction with CPT 88365, CPT 88366, CPT 88368, CPT 88377 for the same probe.

CPT CODE: 88377 CPT Code
Code Description;
Morphometric analysis, in situ hybridization (quantitative or semi-quantitative), manual,
per specimen; each multiplex probe stain procedure
Do not report CPT 88368 or CPT 88377 in conjunction with CPT 88365, CPT 88366, CPT 88367, CPT 88374 for
the same probe 

Reference: www.ama-assn.org/

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