Benign Cutaneous Neoplasms – Definitions & ICD 11 Codes

Definition of Benign Cutaneous Neoplasms: Abnormal growth of the cells that comprise the tissues of the skin, without any evidence of malignancy.

Coded Elsewhere:

• Benign vascular neoplasms of infancy and childhood (2E81.2)

Benign cutaneous melanocytic neoplasms

ICD 11 Code For Benign cutaneous melanocytic neoplasms

  2F20  Benign cutaneous melanocytic neoplasms

Inclusions:

• Mole
• Pigmented naevus
• Benign melanocytic naevus

2F20.0 Common acquired melanocytic naevus

2F20.00 Multiple benign melanocytic naevi

Definition of Multiple benign melanocytic naevi: The presence of multiple benign melanocytic naevi (often taken as more than 20 naevi >2mm in diameter), an independent risk factor for the development of melanoma with highest risk associated with highest numbers of naevi (>100).

2F20.0Y Other specified common acquired melanocytic naevus

2F20.1 Atypical melanocytic naevus

Definition of Atypical melanocytic naevus: Solitary or multiple, slightly raised, pigmented lesions with irregular borders, usually measuring more than 0.6cm in greatest dimension. Morphologically, there is melanocytic atypia and the differential diagnosis from melanoma may be difficult. Patients are at an increased risk for the development of melanoma.

Inclusions:

• Dysplastic naevus, unspecified

2F20.2 Congenital melanocytic naevus

Definition of Congenital melanocytic naevus: Congenital melanocytic naevi are circumscribed areas of skin pigmentation present at birth as a result of abnormal intrauterine proliferation of melanocytes within the dermis, the epidermis or both. They may range in size from a few millimetres to many centimetres in diameter. If their projected or final adult maximal diameter is greater than 20 cm they are termed giant congenital melanocytic naevi.

2F20.20 Giant congenital melanocytic naevus

Definition of Giant congenital melanocytic naevus: A congenital melanocytic naevus (CMN) with a predicted or final adult maximal diameter of 400 mm or more. Giant CMNs are commonly centred on the dorsal surface of the body between the vertex and the buttocks but may occur elsewhere; they may be associated with multiple smaller satellite naevi (congenital or tardive), hypertrichosis, lipomas or benign proliferative nodules. There is a risk of pre-pubertal melanoma within giant CMN or the central nervous system (CNS). Leptomeningeal melanocytosis or focal neuromelanosis, found in 10-15% of cases, is often associated with other CNS tumours, hydrocephalus, epilepsy, arachnoid cysts, or Dandy-Walker malformation.

2F20.2Y Other specified congenital melanocytic naevus

2F20.2Z Congenital melanocytic naevus unspecified

2F20.3 Generalised eruptive melanocytic naevi

Definition of Generalised eruptive melanocytic naevi: This phenomenon describes the rapid simultaneous appearance of multiple melanocytic naevi, often hundreds in number, on previously uninvolved sun-exposed skin. The phenomenon has been linked to immunosuppression, particularly in renal transplant recipients and in individuals receiving cancer chemotherapy, and may be considered a more advanced counterpart of generalised eruptive lentiginosis.

Exclusions:

• Multiple benign melanocytic naevi (2F20.00)
• Generalized eruptive lentiginosis (ED61)

2F20.Y Other specific types of melanocytic naevus

2F20.Z Melanocytic naevus unspecified

Benign keratinocytic acanthomas

Definition of Benign keratinocytic acanthomas: A group of benign discrete epidermal proliferative disorders including seborrhoeic keratosis and clear cell acanthoma.

ICD 11 Code For Benign keratinocytic acanthomas

  2F21  Benign keratinocytic acanthomas

2F21.0 Seborrhoeic keratosis

Definition of Seborrhoeic keratosis: Seborrhoeic keratoses are very common benign neoplasms of epidermal keratinocytes which increase in prevalence and number with age. They are commonly multiple and are very variable in shape and colour. Because of the sometimes intense pigmentation they are frequently mistaken for melanocytic tumours.

Inclusions:

• Basal cell papilloma
• Seborrheic wart

2F21.Y Other specified benign keratinocytic acanthomas

Benign neoplasms of epidermal appendages

Definition of Benign neoplasms of epidermal appendages: A range of benign neoplasms arising from the hair follicle, its associated glands or from sweat glands.

ICD 11 Code For Benign neoplasms of epidermal appendages

  2F22  Benign neoplasms of epidermal appendages

Benign dermal fibrous or fibrohistiocytic neoplasms

Definition of Benign dermal fibrous or fibrohistiocytic neoplasms: Benign dermal neoplasms due to abnormal proliferation of fibroblasts, myofibroblasts or primitive mesenchymal cells.

ICD 11 Code For Benign dermal fibrous or fibrohistiocytic neoplasms

  2F23  Benign dermal fibrous or fibrohistiocytic neoplasms

2F23.0 Dermatofibroma

Definition of Dermatofibroma: A common benign skin tumour which presents as a firm dermal papule or nodule, most commonly on the lower limbs. Histologically it is characterised by coarse, haphazardly arranged collagen bundles and a variable cellular infiltrate including fibrocytes.

2F23.Y Other specified benign dermal fibrous or fibrohistiocytic neoplasms

Benign cutaneous neoplasms of neural or nerve sheath origin

ICD 11 Code For Benign cutaneous neoplasms of neural or nerve sheath origin

  2F24  Benign cutaneous neoplasms of neural or nerve sheath origin

Cherry angioma

ICD 11 Code For Cherry angioma

  2F25  Cherry angioma

Inclusions:

• Campbell de Morgan spot
• Senile angioma

Lobular capillary haemangioma

Definition of Lobular capillary haemangioma: Historically called pyogenic granuloma, this is a common benign proliferation of capillary blood vessels which may be induced by trauma or by certain drugs. It presents as one or more bright red papules or nodules often located around the mouth or on a terminal phalanx in relation to the nail. Bleeding, ulceration and crusting frequently occur. BRAF mutations within vascular endothelial cells may be present, indicating that this is, in at least a proportion of cases, a true neoplastic process.

ICD 11 Code For Lobular capillary haemangioma

  2F26  Lobular capillary haemangioma

Inclusions:

• Lobular capillary haemangioma of skin

Other specified benign cutaneous neoplasms

ICD 11 Code For Other specified benign cutaneous neoplasms

  2F2Y  Other specified benign cutaneous neoplasms

Benign cutaneous neoplasm of unspecified type

ICD 11 Code For Benign cutaneous neoplasm of unspecified type

  2F2Z  Benign cutaneous neoplasm of unspecified type

Benign neoplasm of breast

Definition of Benign neoplasm of breast: A non-metastasizing neoplasm arising from the breast parenchyma.

ICD 11 Code For Benign neoplasm of breast

  2F30  Benign neoplasm of breast

Exclusions:

• Benign neoplasm of skin of breast
• Lipoma (2E80.0)

2F30.0 Tubular adenoma of breast

Definition of Tubular adenoma of breast: A benign, well circumscribed neoplasm that arises from the breast. It is composed entirely of tubular structures that contain epithelial and myoepithelial cells.

2F30.1 Lactating adenoma of breast

Definition of Lactating adenoma of breast: A tubular type adenoma of the breast in which, during pregnancy and lactation, the epithelial cells show extensive secretory changes.

2F30.2 Intraductal papilloma of breast

Definition of Intraductal papilloma of breast: A benign papillary neoplasm that arises anywhere in the ductal system of the breast. It is characterised by fibrovascular structures lined by benign epithelial and myoepithelial proliferations. Intraductal breast papillomas are classified as central, when they arise in large ducts, or peripheral, when they arise in the terminal ductal lobular units.

2F30.3 Benign phyllodes tumour of breast

Definition of Benign phyllodes tumour of breast: A usually unilateral, benign and well circumscribed biphasic neoplasm that arises from the breast. It usually affects middle-aged women. It is characterised by the presence of a double layer of epithelial cells that are arranged in clefts, surrounded by a cellular, monomorphic spindle cell mesenchymal component. Mitoses are rare. Necrotic changes may be present in large tumours.

2F30.4 Fibromatosis of breast

2F30.5 Fibroadenoma of breast

Definition of Fibroadenoma of breast: A benign tumour of the breast characterised by the presence of stromal and epithelial elements. It presents as a painless, solitary, slow growing, firm, and mobile mass. It is the most common benign breast lesion. It usually occurs in women of childbearing age. The majority of fibroadenomas do not recur after complete excision. A slightly increased risk of developing cancer within fibroadenomas or in the breast tissue of patients previously treated for fibroadenomas has been reported.

2F30.6 Extensive adenomatosis of nipple

Definition of Extensive adenomatosis of nipple: Rare benign nipple condition presenting as pruritus, burning or pain symptoms with clinical signs showing a nipple which appears ulcerated, crusting, scaling, indurated and erthymatous. Differential diagnosis: Paget, psoriasis, etc

2F30.Y Other specified benign neoplasm of breast

2F30.Z Benign neoplasm of breast unspecified

Benign non-mesenchymal neoplasms of uterus

Definition of Benign non-mesenchymal neoplasms of uterus: Other non-malignant tumours of the uterus not detailed elsewhere.

ICD 11 Code For Benign non-mesenchymal neoplasms of uterus

  2F31  Benign non-mesenchymal neoplasms of uterus

Exclusions:

• Leiomyoma of uterus (2E86.0)

2F31.0 Benign non-mesenchymal neoplasm of uterus cervix uteri

2F31.00 Cervical Intraepithelial neoplasia grade I

2F31.0Y Other specified benign non-mesenchymal neoplasm of uterus cervix uteri

2F31.0Z Benign non-mesenchymal neoplasm of uterus cervix uteri unspecified

2F31.1 Benign non-mesenchymal neoplasm of uterus corpus uteri

2F31.2 Benign non-mesenchymal neoplasms of uterus other parts

Benign neoplasm of ovary

Definition of Benign neoplasm of ovary: A non-metastasizing neoplasm that arises from the ovary. Representative examples include serous cystadenoma, mucinous cystadenoma, clear cell adenofibroma, benign Brenner tumour, thecoma, and fibroma.

ICD 11 Code For Benign neoplasm of ovary

  2F32  Benign neoplasm of ovary

Coded Elsewhere:

• Struma ovarii (5A02.Y)

2F32.0 Cystic teratoma

Definition of Cystic teratoma: A condition of the ovary, caused by abnormal proliferation due to genetic mutations, abnormal growth or division of germ cells. This condition is characterised by a benign ovarian neoplasm, and abdominal pain, mass or swelling, or abnormal uterine bleeding, and may lead to ovarian torsion or cystic rupture. Confirmation is by imaging.

2F32.1 Ovarian fibroma

Definition of Ovarian fibroma: A condition of the ovary, caused by abnormal proliferation due to genetic mutations, abnormal growth or division of cells. This condition is characterised by a benign sex chord ovarian tumour. Confirmation is by imaging.

2F32.2 Meigs’ Syndrome

Definition of Meigs’ Syndrome: Benign Syndrome including ovarian fibroma, ascites and pleural effusion

2F32.3 Serous ovarian cystadenoma

2F32.Y Other specified benign neoplasm of ovary

2F32.Z Benign neoplasm of ovary unspecified

Benign neoplasm of other or unspecified female genital organs

Definition of Benign neoplasm of other or unspecified female genital organs: A non-metastasizing neoplasm that arises from the female reproductive system. Representative examples include uterine corpus leiomyoma, endocervical polyp, and benign ovarian germ cell tumour.

ICD 11 Code For Benign neoplasm of other or unspecified female genital organs

  2F33  Benign neoplasm of other or unspecified female genital organs

2F33.0 Vulvar intraepithelial neoplasia grade I usual type HPV-associated

Definition of Vulvar intraepithelial neoplasia grade I usual type HPV-associated: A condition of the vulva, characterised by lesion of the squamous vulvar intraepithelial cells, leading to dysplasia, varying degrees of atypia, and carcinoma in situ of the cells. This condition is associated with smoking and immunosuppression, chronic vulvar irritation, or infection with human papillomavirus or herpes simplex virus type 2. Confirmation is by tissue biopsy.

Exclusions:

• Vulvar intraepithelial neoplasia grade II-III, usual type, HPV-associated (2E67.10)
• Vulvar intraepithelial neoplasia grade III, simplex, differentiated type, non-HPV associated (2E67.10)
• Vulvar intraepithelial neoplasia, HPV independent (2F33)

2F33.1 Vaginal intraepithelial neoplasia grade I

Definition of Vaginal intraepithelial neoplasia grade I: A condition characterised by lesions of the squamous vaginal intraepithelial cells, leading to dysplasia, varying degrees of atypia, and abnormal cell growth within one third of the vaginal skin. This condition may be associated with human papillomavirus infection. Confirmation is by the Papanicolaou smear test followed by a biopsy of any abnormal cell growth.

2F33.Y Benign neoplasm of other specified female genital organs

2F33.Z Benign neoplasm of unspecified female genital organs

Benign neoplasm of male genital organs

Definition of Benign neoplasm of male genital organs: A non-metastasizing neoplasm that arises from the male reproductive system. Representative examples include benign prostate phyllodes tumour, benign Sertoli cell tumour, seminal vesicle cystadenoma, and epididymal adenomatoid tumour.

ICD 11 Code For Benign neoplasm of male genital organs

  2F34  Benign neoplasm of male genital organs

Benign neoplasm of urinary organs

Definition of Benign neoplasm of urinary organs: A non-metastasizing neoplasm that arises from the organs that comprise the urinary system. Representative examples include renal oncocytoma, bladder inverted papilloma, and urothelial papilloma.

ICD 11 Code For Benign neoplasm of urinary organs

  2F35  Benign neoplasm of urinary organs

Benign neoplasm of eye or ocular adnexa

ICD 11 Code For Benign neoplasm of eye or ocular adnexa

  2F36  Benign neoplasm of eye or ocular adnexa

Exclusions:

• Benign neoplasm of optic nerve (2A02.3)
• Benign neoplasm of skin of eyelid

Coded Elsewhere:

• Seborrhoeic keratosis (2F21.0)

2F36.0 Benign neoplasm of uvea

Definition of Benign neoplasm of uvea: Abnormal growth of the cells of the choroid without malignant characteristics.

Coded Elsewhere:

• Haemangioma of choroid (2E81.0Y)

2F36.1 Benign neoplasm of iris

2F36.2 Benign neoplasm of ciliary body

2F36.3 Teratoma of orbit

Definition of Teratoma of orbit: This is an encapsulated tumour with tissue or organ components resembling normal derivatives of all three germ layers. This diagnosis is of the cavity or socket of the skull in which the eye and its appendages are situated.

2F36.4 Cysts of eyelid

Coded Elsewhere:

• Epidermoid cyst (EK70.0)

2F36.Y Other specified benign neoplasm of eye or ocular adnexa

2F36.Z Benign neoplasm of eye or ocular adnexa unspecified

Benign neoplasm of endocrine glands

ICD 11 Code For Benign neoplasm of endocrine glands

  2F37  Benign neoplasm of endocrine glands

Exclusions:

• Benign neoplasm of endocrine pancreas (2E92.9)
• Benign neoplasm of thymus (2F01)
• Benign neoplasm of ovary (2F32)
• Benign neoplasm of testis (2F34)
• Benign neoplasm of hypothalamus (2A00.5)

2F37.0 Non-secreting pituitary adenoma

2F37.Y Other specified benign neoplasm of endocrine glands

2F37.Z Benign neoplasm of endocrine glands unspecified

Benign non-mesenchymal neoplasms of other specified site

ICD 11 Code For Benign non-mesenchymal neoplasms of other specified site

  2F3Y  Benign non-mesenchymal neoplasms of other specified site

Benign non-mesenchymal neoplasms of unspecified site

ICD 11 Code For Benign non-mesenchymal neoplasms of unspecified site

  2F3Z  Benign non-mesenchymal neoplasms of unspecified site

Other specified benign neoplasms except of lymphoid haematopoietic central nervous system or related tissues

ICD 11 Code For Other specified benign neoplasms except of lymphoid haematopoietic central nervous system or related tissues

  2F5Y  Other specified benign neoplasms except of lymphoid haematopoietic central nervous system or related tissues

Benign neoplasms except of lymphoid haematopoietic central nervous system or related tissues unspecified

ICD 11 Code For Benign neoplasms except of lymphoid haematopoietic central nervous system or related tissues unspecified

  2F5Z  Benign neoplasms except of lymphoid haematopoietic central nervous system or related tissues unspecified