How To Use CPT Code 82670

CPT 82670 is a code used for the quantitative measurement of total estradiol levels in a patient’s specimen, such as blood. This article will cover the description, procedure, qualifying circumstances, appropriate usage, documentation requirements, billing guidelines, historical information, similar codes, and examples of CPT 82670 procedures.

1. What is CPT 82670?

CPT 82670 is a code used by medical professionals to bill for the laboratory test that measures the level of total estradiol, an estrogenic hormone, in a patient’s specimen. This test is commonly ordered to assess female reproductive function and disorders, as well as male feminization conditions. Estradiol is a form of estrogen that occurs in both men and women and is related to various biological processes, including growth and bone metabolism.

2. 82670 CPT code description

The official description of CPT code 82670 is: Estradiol; total.

3. Procedure

The procedure for CPT 82670 involves the following steps:

1. Collection of the patient’s specimen, such as blood, by the collecting provider.
2. Preparation of the specimen for analysis using an automated analytical instrument.
3. Separation of components in the specimen through a high-pressure liquid chromatograph.
4. Quantification of individual components in a mass spectrometer based on mass to charge ratio.
5. Obtaining a quantitative result for total estradiol levels in the patient’s specimen.

4. Qualifying circumstances

Patients eligible to receive CPT code 82670 services include those who require assessment of their hormonal status related to fertility or other conditions. This may involve evaluating female reproductive function and disorders, such as readiness for in vitro fertilization (IVF) or response to hormone replacement therapy. Additionally, this test may be ordered for male patients to evaluate feminization conditions.

5. When to use CPT code 82670

It is appropriate to bill the 82670 CPT code when a quantitative test for the level of total estradiol in the patient’s specimen, such as blood, is performed. This code should not be used for the measurement of free estradiol levels.

6. Documentation requirements

To support a claim for CPT 82670, the following information should be documented:

• Patient’s demographic information, including age and gender.
• Relevant medical history and clinical indications for ordering the test.
• Details of the specimen collection, including date and time.
• Method used for the analysis, such as liquid chromatography-tandem mass spectrometry (LC-MS/MS).
• Quantitative results of the total estradiol levels in the patient’s specimen.
• Interpretation of the results and any recommendations for further evaluation or treatment.

7. Billing guidelines

When billing for CPT code 82670, keep in mind the following guidelines and tips:

• Some payers may pay separately for collecting the specimen using a code such as 36415.
• Distinguish 82670 from child code 82681, which describes a test for free estradiol.
• For estradiol response panel, see CPT code 80415.
• For other estrogen fractions, see the following codes: estriol, 82677; estrone, 82679; or estrogens, fractionated, 82671.
• For quantitation of total estrogens, see CPT code 82672.

8. Historical information

CPT 82670 was added to the Current Procedural Terminology system on January 1, 1990. The code was changed on January 1, 2021, with the previous descriptor being “Estradiol.”

9. Similar codes to CPT 82670

Five similar codes to CPT 82670 and how they differentiate from it are:

• CPT 82671: This code is used for the measurement of estrogens, fractionated, rather than total estradiol.
• CPT 82672: This code is used for the quantitation of total estrogens, not just estradiol.
• CPT 82677: This code is used for the measurement of estriol levels, a different estrogen fraction.
• CPT 82679: This code is used for the measurement of estrone levels, another estrogen fraction.
• CPT 82681: This code is used for the measurement of free estradiol levels, not total estradiol.

10. Examples

Here are 10 detailed examples of CPT code 82670 procedures:

1. A 35-year-old woman undergoing evaluation for in vitro fertilization (IVF) has her total estradiol levels measured.
2. A 28-year-old woman with irregular menstrual cycles has her total estradiol levels tested to assess her hormonal status.
3. A 45-year-old woman on hormone replacement therapy has her total estradiol levels measured to monitor her response to treatment.
4. A 38-year-old man with suspected feminization syndrome has his total estradiol levels tested to confirm the diagnosis.
5. A 32-year-old woman with polycystic ovary syndrome (PCOS) has her total estradiol levels measured as part of her hormonal evaluation.
6. A 40-year-old woman with a history of infertility has her total estradiol levels tested to determine the cause of her infertility.
7. A 50-year-old woman with menopausal symptoms has her total estradiol levels measured to assess her hormonal status.
8. A 42-year-old man with gynecomastia has his total estradiol levels tested to evaluate the cause of his condition.
9. A 29-year-old woman with a history of recurrent miscarriages has her total estradiol levels measured to assess her hormonal status.
10. A 47-year-old woman with suspected estrogen-producing tumor has her total estradiol levels tested to aid in the diagnosis.