CPT Code For CMP, cpt 80053, cpt code 80053, 80053 cpt code

CPT Code 80053 | Comprehensive Metabolic Panel (CMP)

CPT code 80053 (also known as the CPT code for CMP) describes a comprehensive metabolic panel that measures the levels of 14 different chemicals in a patient’s blood through a laboratory test that involves collecting a blood sample and using various techniques to measure the levels of each chemical.

What Is CPT Code 80053?

CPT 80053 refers to a “Comprehensive metabolic panel,” a laboratory test measuring the levels of 14 different chemicals in a patient’s blood.

These chemicals include albumin, bilirubin, calcium, carbon dioxide (bicarbonate), chloride, creatinine, glucose, alkaline phosphatase, potassium, protein, sodium, alanine amino transferase (SGPT), aspartate amino transferase (SGOT), and blood urea nitrogen (BUN).

To perform this test, a laboratory analyst collects a blood sample from the patient, which can be done through a vein puncture or other methods.

The analyst then uses various techniques to measure the levels of each of these chemicals in the blood.

It is important to note that all 14 components of the panel must be included to report CPT 80053.


The CPT book describes CPT code 80053 as: “Comprehensive metabolic panel.

This panel must include the following: 

  • Albumin (CPT 82040)
  •  Bilirubin, total (CPT 82247)
  •  Calcium, total (CPT 82310)
  •  Carbon dioxide (bicarbonate) (CPT 82374)
  •  Chloride (CPT 82435)
  •  Creatinine (CPT 82565)
  •  Glucose (CPT 82947)
  •  Phosphatase, alkaline (CPT 84075)
  •  Potassium (CPT 84132)
  •  Protein, total (CPT 84155)
  •  Sodium (CPT 84295)
  •  Transferase, alanine amino (ALT) (SGPT) (CPT 84460)
  •  Transferase, aspartate amino (AST) (SGOT) (CPT 84450)
  •  Urea nitrogen (BUN) (CPT 84520).”


The lab analyst performs a test to measure the blood level of 14 chemicals according to the official description of CPT 80053. 

A typical specimen is a serum or blood. The lab analyst may collect the specimen and, if necessary, insert a needle into the patient’s vein and withdraw the blood sample for analysis.

Carefully review the code descriptor to identify the specific tests the panel includes.

CPT code 80053 requires the performance of all 14 components to report. The services inclusive of this test are: 

  • CPT 82040 for albumin;
  •  CPT 82247 for a total bilirubin;
  •  CPT 82310 for total calcium;
  •  CPT 82374 for carbon dioxide or bicarbonate;
  •  CPT 82435 for chloride;
  •  CPT 82565 for creatinine;
  •  CPT 82947 for glucose;
  •  CPT 84075 for alkaline phosphatase;
  •  CPT 84132 for potassium;
  •  CPT 84155 for a total protein;
  •  CPT 84295 for sodium;
  •  CPT 84460 for alanine amino transferase or SGPT;
  •  CPT 84450 for aspartate aminotransferase, or SGOT; and
  •  CPT 84520 for blood urea nitrogen or BUN.

The lab analyst may use a variety of methods to perform each of the panel tests.

The clinician orders this test as part of an annual physical examination or health check.

The panel is an important screening tool and baseline assessment of a patient’s basic physiology.

It provides information about a person’s liver and kidneys, levels of blood glucose and blood proteins, and electrolyte and fluid balance. It helps to diagnose liver or kidney disease, as well as conditions like diabetes.

A clinician may also order a CMP to monitor conditions, such as hypertension, and to check on people taking specific medications known to affect the kidney or liver.

How To Use CPT 80053

To correctly bill the CPT code 80053 for the comprehensive metabolic panel, all tests listed in the code description must be performed.

If any of these tests are not done, they should be reported individually rather than as part of the panel.

If additional tests are performed in addition to those listed in the panel code, both the panel code and the individual codes for the additional tests should be reported.

It may also be necessary to report a separate code, such as CPT 36415, for collecting a venous blood sample through venipuncture to receive a payment if this service is not included in the comprehensive metabolic panel code.

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