How To Use CPT Code 85576

CPT 85576 describes the evaluation of platelet aggregation, or clumping, in a blood specimen after the addition of a specific chemical reagent. This article will cover the description, procedure, qualifying circumstances, appropriate usage, documentation requirements, billing guidelines, historical information, similar codes and billing examples.

1. What is CPT Code 85576?

CPT 85576 can be used to describe the evaluation of platelet aggregation in a blood specimen. This test is performed by a lab analyst who adds a specific chemical reagent to the specimen and uses special instrumentation to assess the level of clumping. Platelet aggregation is an important step in blood clot formation, and this test helps clinicians diagnose platelet dysfunction and bleeding disorders.

2. Official Description

The official description of CPT code 85576 is: ‘Platelet, aggregation (in vitro), each agent.’

3. Procedure

  1. The lab analyst receives a blood specimen and adds a specific chemical reagent to induce platelet aggregation.
  2. Using special instrumentation, the lab analyst evaluates the level of clumping by measuring factors such as increased clarity of the fluid or changes in electrical impedance.
  3. The results of the platelet aggregation test help clinicians assess the patient’s platelet function and diagnose any potential disorders or dysfunctions.

4. Qualifying circumstances

CPT 85576 is typically ordered for patients with symptoms indicative of a bleeding disorder, a low platelet count, or a family history of platelet dysfunction. It can also be used to evaluate platelet dysfunction caused by medication, genetic disorders like von Willebrand’s disease, or other conditions such as uremia. The test is performed by a lab analyst using a specific chemical reagent to induce platelet aggregation.

5. When to use CPT code 85576

CPT code 85576 should be used when a clinician orders a platelet aggregation test with a specific chemical reagent to evaluate platelet function. It is important to bill one unit of CPT 85576 for each test performed with a single reagent. This code should not be used for testing thromboxane metabolites in urine, which requires a different code (84431).

6. Documentation requirements

To support a claim for CPT 85576, the documentation should include:

  • Reason for ordering the test, such as symptoms or family history
  • Specific chemical reagent used for the platelet aggregation test
  • Date of the test
  • Results of the test, including any abnormalities or dysfunctions
  • Pathologist interpretation and report, if applicable

7. Billing guidelines

When billing for CPT 85576, ensure that the test is performed by a lab analyst using a specific chemical reagent to induce platelet aggregation. It is important to bill one unit of CPT 85576 for each test performed with a single reagent. Some payers may also separately reimburse for specimen collection using a venipuncture code (36415). If the pathologist performs the interpretation and report, use modifier 26 to indicate the professional component of the service.

8. Historical information

CPT 85576 was added to the Current Procedural Terminology system on January 1, 1990. There have been no updates or changes to the code since its addition.

9. Examples

  1. A patient with a family history of platelet dysfunction undergoes a platelet aggregation test using epinephrine as the reagent.
  2. A clinician orders a platelet aggregation test with collagen as the reagent for a patient with unexplained bleeding symptoms.
  3. A patient with a low platelet count undergoes a platelet aggregation test using ristocetin as the reagent to assess platelet function.
  4. A platelet aggregation test is performed with adenosine diphosphate as the reagent for a patient on medication that may affect platelet function.
  5. A clinician orders a platelet aggregation test with arachidonic acid as the reagent to evaluate platelet dysfunction in a patient with uremia.
  6. A platelet aggregation test is performed using thrombin as the reagent to assess platelet function in a patient with suspected von Willebrand’s disease.
  7. A patient with symptoms of a bleeding disorder undergoes a platelet aggregation test with a specific chemical reagent to evaluate platelet function.
  8. A clinician orders a platelet aggregation test with a specific chemical reagent for a patient with a suspected medication-induced platelet dysfunction.
  9. A platelet aggregation test is performed using a specific chemical reagent to assess platelet function in a patient with unexplained bleeding symptoms.
  10. A patient with a family history of platelet dysfunction undergoes a platelet aggregation test with a specific chemical reagent to evaluate platelet function.

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