CPT Codes For Cytogenetic Studies

Below is a list summarizing the CPT codes for cytogenetic studies.

CPT Code 88230

CPT 88230 describes tissue culture for non-neoplastic disorders, such as lymphocytes.

CPT Code 88233

CPT 88233 describes skin or another solid tissue biopsy for tissue culture for non-neoplastic disorders.

CPT Code 88235

CPT 88235 describes tissue culture for non-neoplastic disorders, including amniotic fluid or chorionic villus cells.

CPT Code 88237

CPT 88237 describes tissue culture for neoplastic disorders, including bone marrow and blood cells.

CPT Code 88239

CPT 88239 describes tissue culture for neoplastic disorders, such as solid tumors.

CPT Code 88240

CPT 88240 describes each cell line’s cryopreservation, freezing, and storage.

CPT Code 88241

CPT 88241 describes the thawing and expansion of each frozen cell aliquot.

CPT Code 88245

CPT 88245 describes a baseline Sister Chromatid Exchange (SCE) analysis of 20-25 cells for breakage syndromes.

CPT Code 88248

CPT 88248 describes a chromosome analysis for breakage syndromes, including a baseline breakage score of 50-100 cells, a count of 20 cells, and two karyotypes (e.g., for ataxia telangiectasia, Fanconi anemia, fragile X).

CPT Code 88249

CPT 88249 describes chromosome analysis for breakage syndromes, with a score of 100 cells, and exposure to clastogen stress such as diepoxybutane, mitomycin C, ionizing radiation, and UV radiation.

CPT Code 88261

CPT 88261 describes a chromosome analysis that includes a count of five cells and one karyotype with banding.

CPT Code 88262

CPT 88262 describes a chromosome analysis with a count of 15-20 cells, with two karyotypes and banding.

CPT Code 88263

CPT 88263 describes a chromosome analysis that includes a count of 45 cells for mosaicism and two karyotypes with banding.

CPT Code 88264

CPT 88264 describes the analysis of 20-25 cells for chromosome analysis.

CPT Code 88267

CPT 88267 describes a chromosome analysis of amniotic fluid or chorionic villus, with a count of 15 cells and one karyotype with banding.

CPT Code 88269

CPT 88269 describes a chromosome analysis of amniotic fluid cells, counting cells from 6-12 colonies with one karyotype and banding.

CPT Code 88271

CPT 88271 describes molecular cytogenetics using a DNA probe, such as FISH.

CPT Code 88272

CPT 88272 describes the analysis of 3-5 cells for molecular cytogenetics and chromosomal in situ hybridization, including derivatives and markers.

CPT Code 88273

CPT 88273 describes the analysis of 10-30 cells for microdeletions using molecular cytogenetics and chromosomal in situ hybridization.

CPT Code 88274

CPT 88274 describes the analysis of 25-99 cells using interphase in situ hybridization for molecular cytogenetics.

CPT Code 88275

CPT 88275 describes the analysis of 100-300 cells through interphase in situ hybridization for molecular cytogenetics.

CPT Code 88280

CPT 88280 describes additional karyotypes in each study for chromosome analysis.

CPT Code 88283

CPT 88283 describes a chromosome analysis with an additional specialized banding technique, such as NOR or C-banding.

CPT Code 88285

CPT 88285 describes a chromosome analysis with other cells counted for each study.

CPT Code 88289

CPT 88289 describes a chromosome analysis with an additional high-resolution study.

CPT Code 88291

CPT 88291 describes the interpretation and report of cytogenetics and molecular cytogenetics.

CPT Code 88299

CPT 88299 describes an unlisted cytogenetic study.