CPT Codes For Cytogenetic Studies

CPT Codes For Cytogenetic Studies

CPT code range 88230 to 88299 is used for Cytogenetic Studies. These codes are used to report laboratory procedures that involve the analysis of chromosomes to detect genetic abnormalities. These tests are used to diagnose genetic disorders, such as Down syndrome, and to monitor the progress of certain types of cancer.

CPT 88230

CPT code 88230 is used for tissue culture of non-neoplastic disorders, specifically lymphocyte.

This code is used to identify the procedure of culturing lymphocytes, a type of white blood cell, to diagnose and treat specific disorders. This procedure is often used to diagnose and treat autoimmune diseases, infections, and other conditions.

CPT 88233

CPT code 88233 is used for tissue culture for non-neoplastic disorders.

This code is used when a skin or other solid tissue biopsy is performed. The biopsy is then cultured to diagnose any underlying non-neoplastic disorders.

CPT 88235

CPT code 88235 is used for tissue culture of non-neoplastic disorders, such as amniotic fluid or chorionic villus cells.

This code is used to identify the procedure of culturing cells from these sources in order to diagnose and treat specific disorders.

CPT 88237

CPT code 88237 is used for tissue culture of neoplastic disorders, specifically bone marrow and blood cells.

This code is used to identify the procedure of culturing cells from the bone marrow or blood to diagnose and treat neoplastic disorders.

CPT 88239

CPT code 88239 is used for tissue culture of neoplastic disorders, specifically solid tumors.

This code identifies the laboratory procedure of culturing tissue from a solid tumor to diagnose and treat the disorder.

CPT 88240

CPT code 88240 is used for cryopreservation, a process of freezing and storing cells. 

This code is used explicitly for therapeutic cryopreservation of each cell line. For cryopreservation and storage of cells, CPT code 38207 should be used.

CPT 88241

CPT code 88241 is used for each aliquot’s thawing and expansion of frozen cells.

This code should not be used for therapeutic thawing of a previous harvest, which should instead use code 38208.

CPT 88245

CPT code 88245 is used for chromosome analysis to detect breakage syndromes.

This analysis involves a baseline Sister Chromatid Exchange (SCE) of 20-25 cells.

CPT 88248

CPT code 88248 is used for chromosome analysis of breakage syndromes. This includes a baseline breakage score of 50-100 cells, with 20 cells counted and two karyotypes.

This code is typically used for conditions such as ataxia telangiectasia, Fanconi anemia, and fragile X.

CPT 88249

CPT code 88249 is used for chromosome analysis of breakage syndromes.

This analysis involves scoring 100 cells for clastogen stress, which can be caused by diepoxybutane, mitomycin C, ionizing radiation, or UV radiation.

CPT 88261

CPT code 88261 is used for chromosome analysis, which involves counting five cells and creating a karyotype with banding.

This procedure is used to identify any chromosomal abnormalities and can help diagnose genetic disorders.

CPT 88262

CPT code 88262 is used for chromosome analysis, which involves counting 15-20 cells and creating two karyotypes with banding.

This procedure is used to identify any chromosomal abnormalities and can help diagnose genetic disorders.

CPT 88263

CPT code 88263 is used for chromosome analysis, which involves counting 45 cells for mosaicism and creating two karyotypes with banding.

This procedure is used to identify any chromosomal abnormalities or genetic disorders.

CPT 88264

CPT code 88264 is used for chromosome analysis, which involves analyzing 20-25 cells.

This procedure is used to detect any abnormalities in the chromosomes, which can help diagnose genetic disorders.

CPT 88267

CPT code 88267 is used for chromosome analysis of amniotic fluid or chorionic villus, counting 15 cells and producing 1 karyotype with banding.

This code is used to identify any chromosomal abnormalities in the fetus.

CPT 88269

CPT code 88269 is used for chromosome analysis of amniotic fluid cells.

This procedure involves counting cells from 6-12 colonies and creating a karyotype with banding.

CPT 88271

CPT code 88271 is used for molecular cytogenetics, specifically for a DNA probe.

This code is used to detect constitutional chromosomal abnormalities. For genomic sequencing procedures or other molecular multianalyte assays for copy number analysis using circulating cell-free fetal DNA in maternal blood, CPT codes 81420, 81422, and 81479 should be used.

CPT 88272

CPT code 88272 is used for molecular cytogenetics, specifically chromosomal in situ hybridization.

This procedure involves analyzing three to five cells to look for derivatives and markers.

CPT 88273

CPT code 88273 is used for molecular cytogenetics, specifically chromosomal in situ hybridization.

This procedure involves analyzing 10-30 cells to detect microdeletions.

CPT 88274

CPT code 88274 is used for molecular cytogenetics, specifically interphase in situ hybridization.

This procedure involves analyzing 25-99 cells to detect genetic abnormalities.

CPT 88275

CPT code 88275 is used for molecular cytogenetics, specifically interphase in situ hybridization.

This procedure involves analyzing 100-300 cells to detect chromosomal abnormalities.

CPT 88280

CPT code 88280 is used to identify a medical procedure known as chromosome analysis.

This procedure involves the examination of a patient’s chromosomes to identify any abnormalities or genetic disorders.

The 88280 code is used for billing for the analysis of additional karyotypes, which is the study of the number and structure of chromosomes in a cell.

This procedure is often used to diagnose genetic disorders or monitor a patient’s treatment progress.

CPT 88283

CPT code 88283 is used for chromosome analysis with an additional specialized banding technique, such as NOR or C-banding.

This technique is used to identify and analyze the structure of chromosomes, which can help diagnose genetic disorders and other medical conditions.

CPT 88285

CPT code 88285 is used to report chromosome analysis, a laboratory procedure used to examine the number and structure of chromosomes in a sample of cells.

This code is used to report the additional cells counted in each study.

CPT 88289

CPT code 88289 is used for chromosome analysis, specifically an additional high-resolution study.

This type of study is used to identify any abnormalities in the chromosomes, which can help diagnose genetic disorders or other medical conditions.

CPT 88291

CPT code 88291 is used for billing to interpret and report cytogenetics and molecular cytogenetics.

This code is used to document the analysis of chromosomes and interpret the results, identify genetic abnormalities, and diagnose genetic diseases. 

You can use 88291 for billing, interpretation of the analysis results, and preparing a report.

CPT 88299

CPT code 88299 is used to describe an unlisted cytogenetic study.

This code is used when a cytogenetic analysis does not have a specific code assigned to it. It is used to report the professional component of the study, which includes the interpretation of the results.

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