Below are the CPT codes for bone marrow biopsy and their coding guidelines.
Bone Marrow Biopsy CPT Codes
Underneath the descriptions of the codes that can be used for Bone Marrow Biopsy: CPT Code 38222, CPT Code 38221, CPT Code 38220, CPT Code 20225 & CPT Code 20220.
CPT Code 38222
Description of CPT 38222: Diagnostic bone marrow; biopsy/biopsies or aspiration/aspirations.
CPT Code 38221
Description of CPT 38221: Diagnostic bone marrow; biopsy/biopsies.
CPT Code 38220
Description of CPT 38220: Diagnostic bone marrow; aspiration/aspirations.
CPT Code 20225
Description of CPT 20225: Biopsy, bone, trocar, or needle; deep. (e.g. femur or vertebral body).
CPT Code 20220
Description of CPT 20220: Biopsy, bone, trocar, or needle; deep. (e.g. ribs, spinous process, sternum, or ilium)
Coding Guidelines For Bone Marrow Biopsy
CPT code 38220 and CPT code 38221 may only be reported together if the two procedures are performed at separate sites or patient encounters.
Separate sites include bone marrow aspiration and biopsy in different bones or two separate skin incisions over the same bone.
When both a bone marrow biopsy (CPT code 38221) and bone marrow aspiration (CPT code 38220) are performed at the same site through the same skin incision, do not report the bone marrow aspiration, CPT code 38220, in addition to the bone marrow biopsy (CPT code 38221).
Use modifier 50 for bilateral procedures with CPT 38222, CPT 38221 & CPT 38220.