Malignant Neoplasms Of Endocrine Glands

Definition of Malignant Neoplasms Of Endocrine Glands: A malignant neoplasm affecting the endocrine glands. Representative examples include thyroid gland carcinoma, parathyroid gland carcinoma, pituitary gland carcinoma, and adrenal cortex carcinoma.

Exclusions:

Malignant mesenchymal neoplasms

Malignant neoplasms of thyroid gland

Definition of Malignant neoplasms of thyroid gland: A primary or metastatic malignant neoplasm affecting the thyroid gland.

ICD 11 Code For Malignant neoplasms of thyroid gland

2D10 Malignant neoplasms of thyroid gland

Exclusions:

Malignant mesenchymal neoplasms

Coded Elsewhere:

Thyroid lymphoma (2B33.5)

2D10.0 Follicular carcinoma of thyroid gland

Definition of Follicular carcinoma of thyroid gland: A differentiated adenocarcinoma arising from the follicular cells of the thyroid gland. The nuclear features which characterise the thyroid gland papillary carcinoma are absent. Radiation exposure is a risk factor and it comprises approximately 10% to 15% of thyroid cancers. Clinically, it usually presents as a solitary mass in the thyroid gland. It is generally unifocal and thickly encapsulated and shows invasion of the capsule or the vessels. Diagnostic procedures include: thyroid ultrasound and fine needle biopsy.

2D10.1 Papillary carcinoma of thyroid gland

Definition of Papillary carcinoma of thyroid gland: A differentiated adenocarcinoma arising from the follicular cells of the thyroid gland. Radiation exposure is a risk factor and it is the most common malignant thyroid lesion, comprising 75% to 80% of all thyroid cancers in iodine sufficient countries. Diagnostic procedures include: thyroid ultrasound, and fine needle biopsy. Microscopically, the diagnosis is based on the distinct characteristics of the malignant cells, which include enlargement, oval shape, elongation, and overlapping of the nuclei. The nuclei also display clearing or have a ground glass appearance.

2D10.2 Poorly differentiated carcinoma of thyroid gland

2D10.3 Undifferentiated carcinoma of thyroid gland

Definition of Undifferentiated carcinoma of thyroid gland: A primary carcinoma of the thyroid gland composed of undifferentiated cells. The malignant cells demonstrate evidence of epithelial differentiation, either by immunohistochemistry or electron microscopic studies. Microscopically, in the majority of cases there is a mixture of spindle, epithelioid, and giant cells. The vast majority of the patients present with a rapidly enlarging neck mass. The clinical course is invariably aggressive.

Inclusions:

Anaplastic carcinoma of thyroid gland

2D10.4 Medullary carcinoma of thyroid gland

Definition of Medullary carcinoma of thyroid gland: A neuroendocrine carcinoma arising from the C-cells of the thyroid gland. It is closely associated with multiple endocrine neoplasia syndromes. Approximately 10% to 20% of medullary thyroid carcinomas are familial. Patients usually present with a thyroid nodule that is painless and firm. In the majority of cases nodal involvement is present at diagnosis.

2D10.Y Other specified malignant neoplasms of thyroid gland

2D10.Z Malignant neoplasms of thyroid gland unspecified

Definition of Malignant neoplasms of thyroid gland unspecified: Tumours arising from the adrenal cortex include adenomas and carcinomas. These are rare neoplasms but may cause a variety of hormonal symptoms, including hyperaldosteronism, Cushing syndrome, and virilisation. A small fraction of adrenocortical tumours are associated with an inherited tumour syndrome, including Li-Fraumeni syndrome and Carney complex.

Benign and malignant phaeochromocytomas arise in the adrenal medulla and are derived from chromaffin cells of neural crest origin. Phaeochromocytomas may occur in the setting of several hereditary conditions, including multiple endocrine neoplasia types 2a and 2b, von Hippel Lindau disease and neurofibromatosis.

Extra adrenal paragangliomas arise from chromaffin cells in sympathoadrenal and parasympathetic paraganglia. They occur in many parts of the body and can pose a significant challenge to surgeons and oncologists. Some function as chemoreceptors, others are endocrinologically active. Familial paragangliomas are associated with mutations of the mitochondrial complex II genes.

Malignant neoplasms of adrenal gland

ICD 11 Code For Malignant neoplasms of adrenal gland

2D11 Malignant neoplasms of adrenal gland

Exclusions:

Malignant mesenchymal neoplasms

2D11.0 Adenocarcinoma of adrenal gland

2D11.1 Malignant phaeochromocytoma of adrenal gland

2D11.2 Neuroblastoma of adrenal gland

Definition of Neuroblastoma of adrenal gland: Neuroblastomas are malignant tumours that form in certain types of the nerve tissue. It most often begins in the adrenal gland. About 1 out of 3 neuroblastomas start in the adrenal glands and about 1 out of 4 begin in sympathetic nerve ganglia in the abdomen. Most of the rest start in sympathetic ganglia near the spine in the chest or neck, or in the pelvis.

2D11.Y Other specified malignant neoplasms of adrenal gland

2D11.Z Malignant neoplasms of adrenal gland unspecified

Malignant neoplasms of other endocrine glands or related structures

ICD 11 Code For Malignant neoplasms of other endocrine glands or related structures

2D12 Malignant neoplasms of other endocrine glands or related structures

Exclusions:

Malignant neoplasms of adrenal gland (2D11)
Malignant neoplasms of testis (2C80)
Malignant neoplasms of ovary (2C73)
Malignant neoplasm of pancreas (2C10)
Malignant neoplasms of thyroid gland (2D10)
Malignant neoplasms of thymus (2C27)
Malignant mesenchymal neoplasms

2D12.0 Malignant epithelial neoplasms of other endocrine glands or related structures unspecified type

2D12.1 Adenocarcinoma of other endocrine glands or related structures

2D12.Y Other specified malignant neoplasms of other endocrine glands or related structures

2D12.Z Malignant neoplasms of other endocrine glands or related structures unspecified