Malignant Neoplasms Of Female Genital Organs

Definition of Malignant Neoplasms Of Female Genital Organs: A primary or metastatic malignant neoplasm involving the female reproductive system. Representative examples include endometrial carcinoma, cervical carcinoma, ovarian carcinoma, uterine corpus leiomyosarcoma, adenosarcoma, malignant mixed mesodermal (mullerian) tumour, and gestational choriocarcinoma.

Coding Note:

Includes Malignant neoplasm of skin of female genital organs

Exclusions:

Malignant mesenchymal neoplasms

Malignant neoplasms of vulva

Definition of Malignant neoplasms of vulva: Squamous cell carcinoma of the vulva occurs predominantly in the older age group. Although the incidence rate of vulvar intraepithelial neoplasia is increasing, that of squamous cell carcinoma of the vulva is declining, reflecting earlier detection and more successful treatment. In addition to human papillomavirus infection, cigarette smoking is a putative risk factor for vulvar squamous cell carcinoma. There are three known precursor lesions: vulvar intraepithelial neoplasia, lichen sclerosis and chronic granulomatous disease. Other important epithelial malignancies of the vulva are Paget disease and Bartholin gland carcinoma. They are much less common than squamous lesions, and the risk factors are largely unknown. Prominent non-epithelial tumours are malignant melanoma and sarcoma botyoides.

ICD 11 Code For Malignant neoplasms of vulva

2C70 Malignant neoplasms of vulva

Coding Note:

Includes skin of vulva.

Exclusions:

Malignant mesenchymal neoplasms

2C70.0 Basal cell carcinoma of vulva

Definition of Basal cell carcinoma of vulva: A slow growing, locally infiltrating carcinoma that arises from the vulva. It is characterised by the presence of malignant cells that resemble the basal cells that are present in the epidermis.

2C70.1 Melanoma of vulva

2C70.2 Squamous cell carcinoma of vulva

Definition of Squamous cell carcinoma of vulva: An invasive squamous cell carcinoma arising from the vulva. Risk factors include the human papilloma virus and cigarette smoking. Precursor lesions include the vulvar intraepithelial neoplasia, lichen sclerosus with associated squamous cell hyperplasia, and chronic granulomatous vulvar disease such as granuloma inguinale. Symptoms include vulvar pruritus or irritation, discharge, bleeding, and pain. The following morphologic variants have been identified: keratinizing, non-keratinizing, basaloid, warty, verrucous, keratoacanthoma-like, and squamous cell carcinoma with tumour giant cells. Risk factors for recurrence include advanced stage, tumour diameter greater than 2.5 cm, multifocality, capillary-like space involvement, associated vulvar intraepithelial neoplasia grades 2 or 3, and margins of resection involved by tumour.

Coded Elsewhere:

Verrucous squamous cell carcinoma of vulva (2C31.0)

2C70.Y Other specified malignant neoplasms of vulva

Coding Note:

Includes skin of vulva.

2C70.Z Malignant neoplasms of vulva unspecified

Coding Note:

Includes skin of vulva.

Malignant neoplasms of vagina

Definition of Malignant neoplasms of vagina: A primary or metastatic malignant tumour involving the vagina. Representative examples include carcinomas and sarcomas.

ICD 11 Code For Malignant neoplasms of vagina

2C71 Malignant neoplasms of vagina

Exclusions:

Malignant mesenchymal neoplasms

2C71.0 Adenocarcinoma of vagina

Definition of Adenocarcinoma of vagina: An adenocarcinoma arising from the vagina. Morphologic variants include the clear cell, endometrioid, mesonephric, and mucinous adenocarcinoma.

2C71.1 Melanoma of vagina

Definition of Melanoma of vagina: A primary malignant neoplasm of the vagina composed of malignant melanocytes.

2C71.2 Squamous cell carcinoma of vagina

Definition of Squamous cell carcinoma of vagina: A squamous cell carcinoma arising from the vagina. Human papillomavirus infection is associated with the development of vaginal intraepithelial neoplasia and invasive squamous cell carcinoma. Signs and symptoms include painless bleeding, postcoital bleeding, and urinary tract symptoms. Morphologically it resembles squamous cell carcinomas in other anatomic sites.

2C71.Y Other specified malignant neoplasms of vagina

2C71.Z Malignant neoplasms of vagina unspecified

Malignant neoplasms of uterine ligament parametrium or uterine adnexa

ICD 11 Code For Malignant neoplasms of uterine ligament parametrium or uterine adnexa

2C72 Malignant neoplasms of uterine ligament parametrium or uterine adnexa

Exclusions:

Malignant mesenchymal neoplasms

2C72.0 Adenocarcinoma of uterine ligament parametrium or uterine adnexa

2C72.1 Mucinous or serous carcinoma of uterine ligament parametrium or uterine adnexa

2C72.3 Carcinosarcomas of uterine ligament parametrium or uterine adnexa

2C72.Y Other specified malignant neoplasms of uterine ligament parametrium and uterine adnexa

2C72.Z Malignant neoplasms of uterine ligament parametrium or uterine adnexa unspecified

Definition of Malignant neoplasms of uterine ligament parametrium or uterine adnexa unspecified: A primary or metastatic malignant neoplasm involving the ovary. Most primary malignant ovarian neoplasms are either carcinomas (serous, mucinous, or endometrioid adenocarcinomas) or malignant germ cell tumours. Metastatic malignant neoplasms to the ovary include carcinomas, lymphomas, and melanomas.

Malignant neoplasms of ovary

ICD 11 Code For Malignant neoplasms of ovary

2C73 Malignant neoplasms of ovary

Exclusions:

Malignant mesenchymal neoplasms

Coded Elsewhere:

Hereditary breast and ovarian cancer syndrome (2C65)

2C73.0 Carcinomas of ovary

2C73.00 Clear cell adenocarcinoma of ovary

Definition of Clear cell adenocarcinoma of ovary: A malignant glandular epithelial tumour characterised by the presence of clear and hobnail cells. The tumour is highly associated with ovarian endometriosis, pelvic endometriosis and paraendocrine hypercalcemia.

2C73.01 Endometrioid adenocarcinoma of ovary

Definition of Endometrioid adenocarcinoma of ovary: An endometrioid adenocarcinoma arising from the ovary. It comprises 10% to 25% of all primary ovarian carcinomas. Grossly, endometrioid carcinoma may present as a cystic or solid mass. Microscopically, the tumour greatly resembles the appearance of the ordinary type of endometrial adenocarcinoma. As a group, endometrioid carcinoma has a prognosis twice as good as that of serous or mucinous carcinoma.

2C73.02 Low grade serous adenocarcinoma of ovary

Definition of Low grade serous adenocarcinoma of ovary: A slow-growing serous adenocarcinoma that arises from the ovary. It usually originates from borderline neoplastic processes or adenofibromas. It is characterised by the presence of low grade cytologic features and infrequent mitotic figures.

2C73.03 High grade serous adenocarcinoma of ovary

2C73.04 Mucinous adenocarcinoma of ovary

Definition of Mucinous adenocarcinoma of ovary: An invasive adenocarcinoma that arises from the ovary and is characterised by the presence of malignant epithelial cells that contain intracytoplasmic mucin. There is cellular atypia, increased layering of cells, complexity of glands, and papillary formations.

2C73.0Y Other specified carcinomas of ovary

2C73.0Z Carcinomas of ovary unspecified

2C73.1 Dysgerminoma of ovary

Definition of Dysgerminoma of ovary: A malignant germ cell tumour arising from the ovary. Morphologically, it is identical to seminoma and consists of a monotonous population of germ cells with abundant pale cytoplasm and uniform nuclei. The stroma invariably contains chronic inflammatory cells, mostly T-lymphocytes. It responds to chemotherapy or radiotherapy and the prognosis relates to the tumour stage.

Inclusions:

Malignant dysgerminomatous germ cell tumour of ovary

2C73.2 Granulosa cell malignant tumour of ovary

Definition of Granulosa cell malignant tumour of ovary: An aggressive granulosa cell tumour that arises from the ovary and metastasizes to other anatomic sites.

2C73.3 Malignant teratoma of ovary

Definition of Malignant teratoma of ovary: A malignant germ cell tumour arising from the ovary. It usually affects females in their first two decades of life. It contains variable amounts of immature embryonal tissues. Based on the amount of immature neuroepithelial component, immature teratomas are graded from 1 to 3. The stage and grade of the tumour and the grade of the metastatic tumour are the important factors that predict prognosis. The use of cisplatin-based combination chemotherapy has significantly improved the survival rates of the patients.

Coded Elsewhere:

Struma ovarii (5A02.Y)

2C73.4 Serous cystadenoma borderline malignancy of ovary

2C73.5 Endodermal sinus tumour unspecified site female

2C73.Y Other specified malignant neoplasms of the ovary

2C73.Z Malignant neoplasms of ovary unspecified

Definition of Malignant neoplasms of ovary unspecified: Tumours of the fallopian tube are much less common than the corresponding ovarian neoplasms; however, histologically the same surface epithelial-stromal tumour subtypes are recognised. Sex cord-stromal and germ cell tumours are rare. Hydatidiform moles and gestational choriocarcinoma are uncommon complications of tubal ectopic pregnancy. The wolffian adnexal tumour is also infrequent and typically occurs in the leaves of the broad ligament. The risk factors appear similar to those of the ovary. Fallopian tube carcinomas are a component of the hereditary breast-ovarian cancer syndrome caused by BRCA1 and BRCA2 germline mutations.

Malignant neoplasms of fallopian tube

ICD 11 Code For Malignant neoplasms of fallopian tube

2C74 Malignant neoplasms of fallopian tube

Exclusions:

Malignant mesenchymal neoplasms

2C74.0 Adenocarcinoma of fallopian tube

Definition of Adenocarcinoma of fallopian tube: An adenocarcinoma that arises from the fallopian tube. Histologic subtypes include clear cell, endometrioid, serous, and mucinous adenocarcinoma. It spreads to adjacent organs, regional lymph nodes, and peritoneum.

2C74.Y Other specified malignant neoplasms of fallopian tube

2C74.Z Malignant neoplasms of fallopian tube unspecified

Malignant neoplasms of placenta

ICD 11 Code For Malignant neoplasms of placenta

2C75 Malignant neoplasms of placenta

Exclusions:

hydatidiform mole, NOS (JA02)
Malignant mesenchymal neoplasms

2C75.0 Malignant trophoblastic neoplasms of placenta

Definition of Malignant trophoblastic neoplasms of placenta: A diverse group of pregnancy-related tumours characterised by excessive proliferation of trophoblasts. Representative examples include hydatidiform mole, gestational choriocarcinoma, and placental site trophoblastic tumour.

2C75.Y Other specified malignant neoplasms of placenta

2C75.Z Malignant neoplasms of placenta unspecified

Definition of Malignant neoplasms of placenta unspecified: A malignant neoplasm that affects the uterine corpus. Representative examples include endometrial carcinoma, carcinosarcoma, leiomyosarcoma, and adenosarcoma.

Malignant neoplasms of corpus uteri

ICD 11 Code For Malignant neoplasms of corpus uteri

2C76 Malignant neoplasms of corpus uteri

Exclusions:

Endometrial stromal sarcoma, primary site (2B5C)

2C76.0 Endometrial endometrioid adenocarcinoma

2C76.1 Endometrial mucinous adenocarcinoma

2C76.2 Endometrial clear cell adenocarcinoma

2C76.3 Endometrial serous adenocarcinoma

2C76.4 Endometrial mixed adenocarcinoma

2C76.40 Endometrial squamous cell carcinoma

2C76.41 Endometrial small cell carcinoma

2C76.42 Endometrial undifferentiated carcinoma

2C76.43 Carcinosarcoma of uterus

2C76.Y Other specified malignant neoplasms of corpus uteri

2C76.Z Malignant neoplasms of corpus uteri unspecified

Definition of Malignant neoplasms of corpus uteri unspecified: Primary or metastatic malignant neoplasm involving the cervix.

Malignant neoplasms of cervix uteri

ICD 11 Code For Malignant neoplasms of cervix uteri

2C77 Malignant neoplasms of cervix uteri

2C77.0 Squamous cell carcinoma of cervix uteri

Definition of Squamous cell carcinoma of cervix uteri: A squamous cell carcinoma arising from the cervical epithelium. It usually evolves from a precancerous cervical lesion. Increased numbers of sexual partners and human papillomavirus (HPV) infection are risk factors for cervical squamous cell carcinoma. The following histologic patterns have been described: Conventional squamous cell carcinoma, papillary squamous cell carcinoma, transitional cell carcinoma, lymphoepithelioma-like carcinoma, verrucous carcinoma, condylomatous carcinoma and spindle cell carcinoma. Survival is most closely related to the stage of disease at the time of diagnosis.

2C77.1 Adenocarcinoma of cervix uteri

Definition of Adenocarcinoma of cervix uteri: An adenocarcinoma arising from the cervical epithelium. It accounts for approximately 15% of invasive cervical carcinomas. Increased numbers of sexual partners and human papillomavirus (HPV) infection are risk factors. Grossly, advanced cervical adenocarcinoma may present as an exophytic mass, an ulcerated lesion, or diffuse cervical enlargement. Microscopically, the majority of cervical adenocarcinomas are of the endocervical (mucinous) type.

2C77.2 Adenosquamous carcinoma of cervix uteri

2C77.3 Neuroendocrine carcinoma of cervix uteri

2C77.Y Other specified malignant neoplasms of cervix uteri

2C77.Z Malignant neoplasms of cervix uteri unspecified

Malignant neoplasms of uterus part not specified

ICD 11 Code For Malignant neoplasms of uterus part not specified

2C78 Malignant neoplasms of uterus part not specified

Malignant neoplasm involving overlapping sites of female genital organs

ICD 11 Code For Malignant neoplasm involving overlapping sites of female genital organs

2C79 Malignant neoplasm involving overlapping sites of female genital organs

Inclusions:

Malignant neoplasm of female genital organs whose point of origin cannot be classified to any other existing entity

Other specified malignant neoplasms of female genital organs

ICD 11 Code For Other specified malignant neoplasms of female genital organs

2C7Y Other specified malignant neoplasms of female genital organs

Coding Note:

Includes Malignant neoplasm of skin of female genital organs