3A00, 3A01, 3A02, 3A03,

Nutritional Or Metabolic Anaemias – ICD 11 Codes

Iron deficiency anaemia

Definition of Iron deficiency anaemia: A disease caused by chronic or acute bleeding, excessive menstrual bleeding, inadequate intake, substances (in diet or drugs) interfering with iron absorption, malabsorption syndromes, inflammation, infection or blood donation. This disease is characterised by decreased levels of iron present in the body. This disease may present with fatigue, pallor or dizziness. Confirmation is by identification of decreased levels of iron in a blood sample.

ICD 11 Code For Iron deficiency anaemia

3A00  Iron deficiency anaemia

3A00.0 Acquired iron deficiency anaemia due to blood loss

Definition of Acquired iron deficiency anaemia due to blood loss: Chronic blood loss is a possible cause in every case of iron-deficiency anaemia. Iron deficiency anaemia may be caused by acute bleeding in gastrointestinal tract, uterus or genitourinary system, copious menstrual blood losses (menorrhagia) and multiple blood donations. In many tropical countries, infestations with hookworms lead to intestinal blood losses that in some individuals can be considerable. Iron deficiency may also be caused by several circumstances related to “chronic posthaemorrhagic anaemia”. A diagnosis of iron deficiency should always lead to a search for pathologic causes of blood loss (e.g. tumours in the gastrointestinal tract or uterus, especially if uterine bleedings have increased or changed in regularity).

Exclusions:

  • congenital anaemia from fetal blood loss (KA8C)

3A00.01 Chronic posthaemorrhagic anaemia

Definition of Chronic posthaemorrhagic anaemia: Chronic iron-deficiency anaemia from bleeding may be caused by colon cancer, gastric cancer, peptic ulcer, Meckel diverticulum, hiatal hernia with linear erosions, colonic vascular ectasia, colonic polyps, haemangioma, inflammatory bowel disease, tumours in the gastrointestinal tract or uterus, and chronic menorrhagia. Some infants with severe iron deficiency have chronic intestinal blood loss induced by exposure to cow’s milk protein. Repeated phlebotomy for blood tests is a cause of anaemia of prematurity.

3A00.0Z Acquired iron deficiency anaemia due to blood loss unspecified

3A00.1 Acquired iron deficiency anaemia due to low intake

Definition of Acquired iron deficiency anaemia due to low intake: Iron deficiency is probably the most common nutritional deficiency disorder in the world. Iron deficiency anaemia during pregnancy increases perinatal risks for mothers and neonates; and increases overall infant mortality. Severe anaemia is a major risk factor associated with greatly increased morbidity and mortality for young children and pregnant women. Prompt recognition of the condition, treatment and clinical follow-up of individuals, are crucial in avoiding complications such as high-output heart failure. Maternal iron deficiency during pregnancy increases the risk of iron deficiency in the infant. In less developed countries, the prevalence of iron deficiency during pregnancy is higher than in developed countries, and iron supplementation during pregnancy is beneficial.

3A00.2 Acquired iron deficiency anaemia due to decreased absorption

3A00.3 Acquired iron deficiency anaemia due to increased requirement

3A00.Y Other specified iron deficiency anaemia

3A00.Z Iron deficiency anaemia unspecified

Definition of Iron deficiency anaemia unspecified: A disease caused by inadequate dietary intake of vitamin B12, impaired absorption of vitamin B12, surgical removal of the small bowel, coeliac disease or inherited mutations affecting absorption of vitamin B12. This disease is characterised by decreased levels of vitamin B12 in the body presenting with or without anaemia. This disease may present with fatigue, pallor, dizziness, seizures, or symptoms of dementia. Confirmation is by identification of decreased levels of vitamin B12 in a blood sample.

Megaloblastic anaemia due to vitamin B12 deficiency

ICD 11 Code For Megaloblastic anaemia due to vitamin B12 deficiency

  3A01  Megaloblastic anaemia due to vitamin B12 deficiency

3A01.0 Hereditary Vitamin B12 deficiency anaemia

Definition of Hereditary Vitamin B12 deficiency anaemia: This is a hereditary low blood level of vitamin B12. It can cause permanent damage to nervous tissue if left untreated long enough. Vitamin B12 itself was discovered through investigation of pernicious anaemia, which is an autoimmune disease that destroys parietal cells in the stomach that secrete intrinsic factor.

3A01.1 Neonatal vitamin B12 deficiency anaemia

Definition of Neonatal vitamin B12 deficiency anaemia: A disease caused by a lack of vitamin B12 in the mother, which is passed onto the fetus in the antenatal period or to the neonate during breast feeding. This disease is characterised by decreased levels of vitamin B12. This disease may present with increased risk of birth defects or preterm delivery, anaemia, irritability, failure to thrive or apathy. Confirmation is by identification of low levels of vitamin B12 in a blood sample.

Exclusions:

  • Hereditary Vitamin B12 deficiency anaemia (3A01.0)

3A01.2 Vitamin B12 deficiency anaemia due to low intake

Definition of Vitamin B12 deficiency anaemia due to low intake: A disease caused by insufficient intake of vitamin B12 into the body. This disease is characterised by low levels of vitamin B12 leading to low levels of red blood cells. This disease may present with pallor, fatigue, or shortness of breath. Confirmation is by identification of low levels of vitamin B12 and red blood cell count in a blood sample.

3A01.3 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency

Exclusions:

  • Vitamin B12 deficiency anaemia due to congenital intrinsic factor deficiency (3A01)

3A01.30 Pernicious anaemia

Definition of Pernicious anaemia: Biermer’s disease, also called acquired pernicious anaemia, is a disorder in vitamin B12 (cobalamin) absorption characterised by megaloblastic anaemia and gastrointestinal symptoms, and that can lead to neurological abnormalities.

3A01.3Y Other specified vitamin B12 deficiency anaemia due to intrinsic factor deficiency

3A01.4 Vitamin B12 deficiency anaemia due to intestinal disease

Definition of Vitamin B12 deficiency anaemia due to intestinal disease: A number of intestinal disorders can also cause vitamin B12 (cobalamin) deficiency. These include severe pancreatic diseases and small bowel diseases such as malabsorption, ileal disease (including tuberculous ileitis, lymphoma, amyloid, long-term survivors of pelvic irradiation), extensive small bowel resection or bypass, gastric surgery/reconstruction for obesity (bariatric surgery) and Crohn’s disease. When jejunal blind loops are present, bacterial overgrowth within the loops competes for cobalamin, leading to cobalamin deficiency. Although not as common currently, infestation with the fish tapeworm, Diphyllobothrium latum, was once a classic cause of cobalamin deficiency.

3A01.5 Drug-induced vitamin B12 deficiency anaemia

3A01.Y Other specified megaloblastic anaemia due to vitamin B12 deficiency

3A01.Z Megaloblastic anaemia due to vitamin B12 deficiency unspecified

Folate deficiency anaemia

ICD 11 Code For Folate deficiency anaemia

  3A02  Folate deficiency anaemia

3A02.0 Hereditary folate deficiency anaemia

3A02.1 Folate deficiency anaemia due to low intake

3A02.2 Folate deficiency anaemia due to increased requirements

3A02.3 Folate deficiency anaemia due to decreased intestinal absorption

Definition of Folate deficiency anaemia due to decreased intestinal absorption: A disease caused by determinants affecting intestinal absorption of folate arising after birth. This disease is characterised by low levels of folate in the body leading to incomplete formation of red blood cells resulting in large numbers of immature and incompletely developed red blood cells. This disease may present with fatigue, muscle weakness, loss of appetite, weight loss, diarrhoea, nausea, tachycardia or extremity paraesthesia. Confirmation is by identification of low folate levels in a blood sample.

3A02.4 Drug-induced folate deficiency anaemia

3A02.Y Other specified folate deficiency anaemia

3A02.Z Folate deficiency anaemia unspecified

Definition of Folate deficiency anaemia unspecified: A disease caused by nutritional and metabolic determinants leading to anaemia. This disease is characterised by decreased levels of red blood cells within the body. This disease may present with fatigue, pallor or dizziness. Confirmation is by identification of a decreased red blood cell count in a blood sample.

Other nutritional or metabolic anaemias

ICD 11 Code For Other nutritional or metabolic anaemias

  3A03  Other nutritional or metabolic anaemias

Coded Elsewhere:

  • Disorders of pyrimidine metabolism (5C55.1)
  • Lesch-Nyhan syndrome (5C55.01)

3A03.0 Hereditary orotic aciduria

Definition of Hereditary orotic aciduria: Hereditary orotic aciduria is an extremely rare (less than 20 cases identified worldwide) autosomal recessive disorder characterised by retarded growth, anaemia and excessive urinary excretion of orotic acid. It is due to a severe deficiency in the activity of the pyrimidine pathway enzyme uridine 5′-monophosphate (UMP) synthase (bifunctional enzyme containing two activities: orotate phosphoribosyltransferase and orotidine 5′-monophosphate decarboxylase), coded by a single gene (UMPS) localised to chromosome 3q13.

3A03.1 Protein deficiency anaemia

Definition of Protein deficiency anaemia: A disease caused by low levels of protein within the body. This disease is characterised by a low red blood cell count in the blood. This disease may present with pallor, fatigue, or shortness of breath. Confirmation is by identification of a low red blood cell count in a blood sample.

Exclusions:

  • Lesch-Nyhan syndrome (5C55.01)

3A03.2 Scorbutic anaemia

Definition of Scorbutic anaemia: Scorbutic anaemia, is a common finding in infants and young children with scurvy and is related to impaired iron absorption and coexistent haematopoietic nutrient deficiencies including iron, vitamin B12 and folate.

3A03.3 Copper deficiency anaemia

Definition of Copper deficiency anaemia: Anaemia due to copper deficiency arises from impaired utilization of iron and is therefore a conditioned form of iron deficiency anaemia.

3A03.4 Acquired other vitamin B deficiency anaemia

Definition of Acquired other vitamin B deficiency anaemia: A disease caused by a lack of B vitamins in the body arising after birth. This disease is characterised by low levels of B vitamins leading to low levels of red blood cells in the body. This disease may present with pallor, fatigue, or shortness of breath. Confirmation is by identification of low red blood cell count and low B vitamin counts in a blood sample.

3A03.40 Acquired pyridoxine deficiency anaemia

Definition of Acquired pyridoxine deficiency anaemia: A disease caused by determinants arising after birth. This disease is characterised by low levels of pyridoxine (vitamin B6) leading to low levels of red blood cells in the body. This disease may present with fatigue, muscle weakness, loss of appetite, weight loss, diarrhoea, nausea, fast heartbeat or numbness in extremities. Confirmation is by identification of low levels of pyridoxine and low red blood cell count in a blood sample.

3A03.41 Acquired riboflavin deficiency anaemia

Definition of Acquired riboflavin deficiency anaemia: A disease caused by determinants arising after birth. This disease is characterised low levels of riboflavin (vitamin B2) leading to low levels of red blood cells in the body. This disease may present with fatigue, muscle weakness, loss of appetite, weight loss, diarrhoea, nausea, fast heartbeat or numbness in extremities. Confirmation is by identification of low levels of riboflavin and low red blood cell count in a blood sample.

3A03.42 Acquired thiamine deficiency anaemia

Definition of Acquired thiamine deficiency anaemia: A disease caused by a lack of thiamine arising after birth. This disease is characterised low levels of thiamine in the body leading to low levels of red blood cells. This disease may present with fatigue, muscle weakness, loss of appetite, weight loss, diarrhoea, nausea, fast heartbeat or numbness in extremities. Confirmation is by identification of low levels of thiamine and low red blood cell count in a blood sample.

3A03.4Y Other specified acquired other vitamin B deficiency anaemia

3A03.5 Acquired vitamin A deficiency anaemia

3A03.6 Acquired vitamin E deficiency anaemia

Inclusions:

  • Haemolytic anaemia due to vitamin E deficiency

3A03.Y Other and unspecified nutritional or metabolic anaemia

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