Viral Hepatitis – Definitions & ICD 11 Codes

Definition of Viral Hepatitis: A group of liver diseases caused by infection with one or more of the five hepatitis viruses, hepatitis A virus, hepatitis B virus, hepatitis C virus, hepatitis D virus and hepatitis E viruses. The infection may be recent and present for less than 6 months (acute hepatitis) or present for more than 6 months (chronic hepatitis), in which case progression to cirrhosis and liver cancer can occur. Transmission is by the faecal-oral route including water contamination, sexual transmission, blood and body fluid contamination (parenteral spread) and from mother to baby at the time of birth (vertical transmission). Depending on the virus, diagnosis is confirmed by detection of specific viral antigens, anti-viral antibodies or viral nucleic acids in serum.

Exclusions:

  • Herpes simplex hepatitis (1F00)
  • Autoimmune hepatitis (DB96.0)
  • Non-alcoholic steatohepatitis (DB92.1)

Coded Elsewhere:

  • Viral hepatitis complicating pregnancy, childbirth or the puerperium (JB63.4)
  • Congenital viral hepatitis (KA62.9)

Acute viral hepatitis

Definition of Acute viral hepatitis: A group of liver diseases characterised by liver inflammation and fibrosis, caused by more than 6 months of infection with one or more of hepatitis B virus, hepatitis C virus and hepatitis D virus, with or without HIV. Even at stage of cirrhosis there are often no symptoms. Otherwise, clinical features include fatigue, hard liver edge and complications of cirrhosis (muscle wasting, ascites, splenomegaly/portal hypertension). Transmission of hepatitis B and C viruses is by blood and body fluid contamination, sexual transmission, and from mother to baby at the time of birth (vertical transmission). In addition to detection of specific antigens (HBsAg) and antibodies (anti-HCV), diagnostic assessment requires assay of viral nucleic acids (HBV DNA, HCV RNA etc).

ICD 11 Code For Acute viral hepatitis

  1E50  Acute viral hepatitis

Exclusions:

  • Infectious liver disease (DB90)
  • Acute or subacute hepatic failure (DB91)
  • Chronic viral hepatitis (1E51)

Coded Elsewhere:

  • Cytomegaloviral hepatitis (1D82.0)
  • Epstein-Barr viral hepatitis (DB90.Y)

Acute hepatitis A

Definition of Acute hepatitis A: Acute liver injury and inflammation caused by recent and short-term (less than 6 months) infection with hepatitis A virus (HAV). Transmission is by the faecal-oral route. Diagnosis is confirmed by presence of IgM-anti-HAV in serum. Clinical features, if they occur, are characterised by anorexia, nausea and fever, with jaundice in severer cases.

ICD 11 Code For Acute hepatitis A

1E50.0 Acute hepatitis A

Exclusions:

  • Infectious liver disease (DB90)
  • Acute or subacute hepatic failure (DB91)

1E50.1 Acute hepatitis B

Definition of Acute hepatitis B: Acute liver injury and inflammation caused by recent and short-term (less than 6 months) infection with hepatitis B virus (HBV). Transmission is by sexual, blood and body fluid contamination (parenteral spread), and from mother to baby at the time of birth (vertical transmission). Diagnosis is confirmed by presence of recent acquisition of HBsAg, ideally with IgM-anti-HBc in serum. Clinical features, if they occur, are characterised by anorexia, nausea and fever, with jaundice in severe cases.

1E50.2 Acute hepatitis C

Definition of Acute hepatitis C: Acute liver injury and inflammation caused by recent and short-term (less than 6 months) infection with hepatitis C virus (HCV). Transmission is by blood and body fluid contamination (parenteral spread) in most cases, and rarely by sexual spread or from mother to baby at the time of birth (vertical transmission). Diagnosis is confirmed by presence of recent acquisition of anti-HCV with presence of HCV RNA in serum. Clinical features occur in a minority of cases and are characterised by anorexia, nausea and fever, rarely with jaundice. A high proportion of cases (>70%) develop chronic HCV infection, with liver disease of varying severity.

Coded Elsewhere:

  • Necrolytic acral erythema (EA20)

1E50.3 Acute hepatitis D

Definition of Acute hepatitis D: Acute liver injury and inflammation caused by recent and short-term (less than 6 months) infection with hepatitis D virus (HDV). Transmission only occurs in someone with chronic HBV infection (super-infection) or at the same time as acute hepatitis B (co-infection), and is by blood and body fluid contamination (parenteral spread), and sexual spread. Diagnosis is confirmed by serum IgM-anti-HDV. Clinical features, if they occur, are characterised by anorexia, nausea and fever, with jaundice in severe cases. Acute liver failure occurs in some cases, and a high proportion of cases develops chronic HDV infection.

Coded Elsewhere:

  • Acute hepatitis B with Hepatitis D virus co-infection (1E50.1)

1E50.4 Acute hepatitis E

Definition of Acute hepatitis E: A disease of the liver, caused by an acute infection with hepatitis E virus. This disease is characterised by nausea. Transmission is commonly by the faecal-oral route. Confirmation is by detection of anti-hepatitis E virus IgM antibodies in an individual’s serum.

1E50.Y Other specified acute viral hepatitis

1E50.Z Acute viral hepatitis unspecified

Chronic viral hepatitis

Definition of Chronic viral hepatitis: A disease of the liver, caused by a chronic infection with a hepatotropic virus such as hepatitis B,C,D virus, with or without HIV (for six months or longer). This disease is characterised by fatigue, joint and muscle pain, jaundice, or urine of dark yellow colour. Transmission is by sexual contact, or direct contact with contaminated blood or body fluids. Confirmation is by detection of anti-hepatitis antibodies in the individual’s serum.

ICD 11 Code For Chronic viral hepatitis

  1E51  Chronic viral hepatitis

Exclusions:

  • Alcoholic liver disease (DB94)
  • Autoimmune hepatitis (DB96.0)
  • Non-alcoholic fatty liver disease (DB92)

1E51.0 Chronic hepatitis B

Definition of Chronic hepatitis B: A liver disease characterised by liver inflammation and fibrosis caused by more than 6 months of infection with the hepatitis B virus. Even at stage of cirrhosis there are often no symptoms. Otherwise, clinical features include fatigue, hard liver edge and complications of cirrhosis (muscle wasting, ascites, splenomegaly/portal hypertension). Transmission is by blood and body fluid contamination, sexual transmission, and from mother to baby at the time of birth (vertical transmission). Confirmation of the diagnosis is by detection of HBsAg, but assessment of severity, prognosis and indication for treatment requires quantification of HBV DNA in serum.

Coded Elsewhere:

  • Chronic hepatitis B, co-infected with hepatitis D virus (1E51.2)
  • Hepatitis B surface antigen [HBsAg] carrier (1E51.Y)

1E51.00 Chronic hepatitis B with human immunodeficiency virus co-infection

Definition of Chronic hepatitis B with human immunodeficiency virus co-infection: A liver disease characterised by liver inflammation and fibrosis caused by more than 6 months of infection with the hepatitis B virus and with the human immunodeficiency virus (HIV). Clinical features include fatigue, hard liver edge and complications of cirrhosis (muscle wasting, ascites, splenomegaly/portal hypertension), and outcomes, including hepatocellular carcinoma are worse than for hepatitis B without HIV infection.

1E51.0Y Other specified chronic hepatitis B

1E51.0Z Chronic hepatitis B unspecified

1E51.1 Chronic hepatitis C

Definition of Chronic hepatitis C: A liver disease characterised by liver inflammation and fibrosis caused by more than 6 months of infection with the hepatitis C virus. Even at stage of cirrhosis there may be no symptoms. Otherwise, clinical features include fatigue and impaired quality of life, hard liver edge and complications of cirrhosis (muscle wasting, ascites, splenomegaly/portal hypertension). Chronic hepatitis C increases the risks of type 2 diabetes mellitus and cardiovascular disease, which contribute to increased all-cause mortality. Transmission is by blood and body fluid contamination, rarely by sexual transmission and from mother to baby at the time of birth (vertical transmission). Confirmation of the diagnosis is by detection of HCV RNA in the presence of a positive anti-HCV in serum.

Exclusions:

  • Non-alcoholic fatty liver disease (DB92)

Coded Elsewhere:

  • Chronic hepatitis B, co-infected with hepatitis C virus (1E51.0Y)
  • Chronic hepatitis B, co-infected with hepatitis C virus and hepatitis D virus (1E51.0Y)

1E51.2 Chronic hepatitis D

Coded Elsewhere:

  • Chronic hepatitis B, co-infected with hepatitis C virus and hepatitis D virus (1E51.0Y)

1E51.3 Chronic hepatitis E

1E51.Y Other specified chronic viral hepatitis

1E51.Z Chronic viral hepatitis unspecified

Viral hepatitis unspecified

ICD 11 Code For Viral hepatitis unspecified

  1E5Z  Viral hepatitis unspecified

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