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Official Description

Biopsy, muscle; superficial

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

An incisional biopsy of muscle tissue, designated by CPT® Code 20200, involves the surgical removal of a small sample from the superficial layer of muscle. This procedure is primarily utilized for diagnostic purposes, allowing healthcare providers to investigate various muscle-related diseases. Conditions such as muscular dystrophy, myasthenia gravis, polymyositis, dermatomyositis, amyotrophic lateral sclerosis (ALS), Friedreich's ataxia, and parasitic infections like trichinosis or toxoplasmosis can be evaluated through this biopsy. The process begins with the careful cleansing of the intended biopsy site to minimize the risk of infection. Following this, a precise incision is made in the muscle to extract a tissue sample, which is then sent for pathology examination to determine the presence of any underlying conditions. It is important to note that CPT® Code 20200 is specifically used for biopsies involving a superficial incision, while CPT® Code 20205 is reserved for deeper muscle biopsies that require more extensive tissue dissection.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The procedure of a superficial muscle biopsy, coded as CPT® 20200, is indicated for the evaluation of various muscle disorders. The following conditions may warrant this procedure:

  • Muscular Dystrophy - A group of genetic diseases characterized by progressive weakness and degeneration of the skeletal muscles.
  • Myasthenia Gravis - An autoimmune disorder that leads to varying degrees of weakness of the skeletal muscles.
  • Polymyositis - An inflammatory disease causing muscle weakness, particularly affecting the proximal muscles.
  • Dermatomyositis - An inflammatory condition characterized by muscle weakness and a distinctive skin rash.
  • Amyotrophic Lateral Sclerosis (ALS) - A progressive neurodegenerative disease affecting nerve cells in the brain and spinal cord, leading to loss of muscle control.
  • Friedreich's Ataxia - A hereditary degenerative disease that affects the nervous system and the heart, leading to progressive loss of coordination and muscle strength.
  • Trichinosis - A parasitic disease caused by eating raw or undercooked meat infected with larvae of the Trichinella worm.
  • Toxoplasmosis - An infection caused by the Toxoplasma gondii parasite, which can affect muscle tissue among other organs.

2. Procedure

The procedure for a superficial muscle biopsy involves several critical steps to ensure accurate tissue sampling. First, the healthcare provider identifies the appropriate site for the biopsy based on clinical evaluation and imaging studies if necessary. Once the site is determined, the area is thoroughly cleansed with an antiseptic solution to reduce the risk of infection. Following this preparation, a local anesthetic is administered to numb the area, ensuring patient comfort during the procedure. After the anesthesia takes effect, a small incision is made in the skin over the muscle, allowing access to the underlying tissue. The provider carefully dissects through the layers of tissue to reach the superficial muscle, where a small sample is excised. This sample is then placed in a sterile container and sent to a pathology lab for examination. The incision is subsequently closed, typically with sutures or adhesive strips, and a sterile dressing is applied to protect the site during the healing process.

3. Post-Procedure

After the superficial muscle biopsy, patients are usually monitored for a short period to ensure there are no immediate complications, such as excessive bleeding or infection. Instructions for post-procedure care are provided, which may include keeping the biopsy site clean and dry, avoiding strenuous activities, and monitoring for signs of infection, such as increased redness, swelling, or discharge. Patients may also be advised on pain management strategies, which can include over-the-counter pain relievers. Follow-up appointments may be scheduled to discuss the pathology results and any further necessary treatment based on the findings.

Short Descr MUSCLE BIOPSY SUPERFICIAL
Medium Descr BIOPSY MUSCLE SUPERFICIAL
Long Descr Biopsy, muscle; superficial
Status Code Active Code
Global Days 000 - Endoscopic or Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Hospital Part B services paid through a comprehensive APC
ASC Payment Indicator Surgical procedure on ASC list in CY 2007; payment based on OPPS relative payment weight.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P6B - Minor procedures - musculoskeletal
MUE 2
CCS Clinical Classification 159 - Other diagnostic procedures on musculoskeletal system
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
52 Reduced services: under certain circumstances a service or procedure is partially reduced or eliminated at the discretion of the physician or other qualified health care professional. under these circumstances the service provided can be identified by its usual procedure number and the addition of modifier 52, signifying that the service is reduced. this provides a means of reporting reduced services without disturbing the identification of the basic service. note: for hospital outpatient reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well-being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
F9 Right hand, fifth digit
GC This service has been performed in part by a resident under the direction of a teaching physician
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
LT Left side (used to identify procedures performed on the left side of the body)
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
RT Right side (used to identify procedures performed on the right side of the body)
SG Ambulatory surgical center (asc) facility service
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
Date
Action
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2024-01-01 Changed Short Description changed.
Pre-1990 Added Code added.
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