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Official Description

Removal and replacement of phrenic nerve stimulator, including vessel catheterization, all imaging guidance, and interrogation and programming, when performed; pulse generator

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 33287 involves the removal and replacement of a phrenic nerve stimulator, which is a medical device implanted to assist patients with moderate to severe central sleep apnea (CSA) by stimulating the diaphragm to contract, thereby facilitating rhythmic breathing. This procedure is essential for patients who rely on the stimulator for respiratory support. The process begins with an incision made over the existing device located in its subcutaneous pocket. The surgeon carefully dissects the surrounding tissue to free the device and its lead(s) from any adhesions. Once the existing pulse generator is removed, the surgical team assesses the pocket to determine if any revisions are necessary before placing a new generator. The existing lead(s) are then reconnected to the new device, and the pocket is subsequently closed. This procedure may also involve additional steps for the removal and replacement of stimulation or sensing lead(s), which are critical components of the phrenic nerve stimulator system. The entire process is performed under imaging guidance to ensure precision and safety, and it includes interrogation and programming of the new device to ensure optimal functionality for the patient.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The removal and replacement of a phrenic nerve stimulator, as described by CPT® Code 33287, is indicated for patients who have a previously implanted phrenic nerve stimulator system that is no longer functioning effectively or has reached the end of its operational life. This procedure is specifically performed for individuals diagnosed with moderate to severe central sleep apnea (CSA), where the device is essential for maintaining adequate respiratory function during sleep.

  • Moderate to Severe Central Sleep Apnea (CSA) The procedure is indicated for patients experiencing significant breathing interruptions during sleep due to CSA, necessitating the use of a phrenic nerve stimulator to assist in diaphragm contraction and improve breathing patterns.

2. Procedure

The procedure for the removal and replacement of a phrenic nerve stimulator involves several critical steps to ensure the safe and effective transition to a new device.

  • Step 1: Incision and Exposure An incision is made over the existing device located in its subcutaneous pocket. This initial step is crucial as it allows the surgeon to access the implanted phrenic nerve stimulator and its associated lead(s). Care is taken to minimize tissue damage during this process.
  • Step 2: Disconnection and Removal Once the device is exposed, the surgeon carefully frees the device and lead(s) from the surrounding tissue. The lead(s) are then disconnected from the existing pulse generator, which is subsequently removed from the pocket. This step may involve assessing the condition of the pocket to determine if any revisions are necessary before placing a new generator.
  • Step 3: Placement of New Generator After the existing generator is removed, a new pulse generator is placed in the pocket. The surgeon ensures that the pocket is adequately prepared for the new device, which may include making any necessary adjustments to accommodate the new generator.
  • Step 4: Reconnection of Lead(s) The existing lead(s) are reconnected to the new pulse generator. This step is critical as it ensures that the stimulation system is fully operational and ready to assist the patient in maintaining proper respiratory function.
  • Step 5: Closure Finally, the incision site is closed, completing the procedure. The surgeon ensures that the area is properly sutured to promote healing and minimize the risk of infection.

3. Post-Procedure

After the removal and replacement of the phrenic nerve stimulator, patients are typically monitored for any immediate complications related to the surgery. Post-procedure care may include pain management, wound care instructions, and follow-up appointments to assess the functionality of the new device. Patients may also undergo programming and interrogation of the new pulse generator to ensure it is functioning correctly and providing the necessary stimulation for effective breathing. It is essential for patients to report any unusual symptoms or discomfort during their recovery period to their healthcare provider.

Short Descr RMV&RPLCMT PHRNC NRV STIM PG
Medium Descr RMVL&RPLCMT PHRENIC NRV STIMULATOR PLS GENERATOR
Long Descr Removal and replacement of phrenic nerve stimulator, including vessel catheterization, all imaging guidance, and interrogation and programming, when performed; pulse generator
Status Code Active Code
Global Days 090 - Major Surgery
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Hospital Part B services paid through a comprehensive APC
ASC Payment Indicator Device-intensive procedure added to ASC list in CY 2008 or later; paid at adjusted rate.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) none
MUE 1

This is a primary code that can be used with these additional add-on codes.

33277 Add On Code Resequenced Code MPFS Status: Active Code APC N ASC N1 Insertion of phrenic nerve stimulator transvenous sensing lead (List separately in addition to code for primary procedure)
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
GC This service has been performed in part by a resident under the direction of a teaching physician
Date
Action
Notes
2024-01-01 Added Code Added.
Code
Description
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