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Official Description

Destruction of lesion(s), penis (eg, condyloma, papilloma, molluscum contagiosum, herpetic vesicle), simple; chemical

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 54050 refers to the procedure for the destruction of lesions on the penis, which may include various types of growths such as condyloma, papilloma, molluscum contagiosum, and herpetic vesicles. This procedure is categorized as a simple chemical destruction method, where the physician employs a chemical agent, such as silver nitrate or another suitable compound, to eliminate the lesions. The process begins with a thorough examination of the lesions to determine the most effective destruction method. Local anesthesia may be administered to ensure patient comfort during the procedure. The physician has several options for lesion destruction, including chemical methods, electrodessication, cryosurgery, laser surgery, and surgical excision, each tailored to the specific characteristics of the lesions being treated. The choice of technique depends on factors such as the type, size, and location of the lesions, as well as the overall health of the patient. This code specifically captures the use of chemical agents for lesion destruction, distinguishing it from other methods that may involve more complex techniques or extensive procedures.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The procedure associated with CPT® Code 54050 is indicated for the treatment of various lesions on the penis. These include:

  • Condyloma - A type of genital wart caused by human papillomavirus (HPV).
  • Papilloma - Benign epithelial tumors that can appear on the skin or mucous membranes.
  • Molluscum contagiosum - A viral infection that results in raised, pearl-like lesions on the skin.
  • Herpetic vesicle - Fluid-filled blisters caused by the herpes simplex virus.

2. Procedure

The procedure for CPT® Code 54050 involves several key steps to ensure effective destruction of the lesions:

  • Step 1: Examination of Lesions - The physician begins by thoroughly examining the lesions on the penis to assess their type, size, and location. This evaluation is crucial for determining the most appropriate method of destruction.
  • Step 2: Administration of Local Anesthesia - To minimize discomfort during the procedure, local anesthesia may be administered to the patient. This step is essential for ensuring that the patient remains comfortable throughout the treatment.
  • Step 3: Chemical Application - The physician applies a chemical agent, such as silver nitrate or another suitable compound, directly to the lesions. This chemical destruction method is designed to effectively eliminate the targeted lesions while preserving surrounding healthy tissue.
  • Step 4: Monitoring and Follow-Up - After the chemical application, the physician monitors the area for any immediate reactions. Follow-up care may be discussed, including instructions for wound care and signs of potential complications.

3. Post-Procedure

Post-procedure care for patients undergoing CPT® Code 54050 typically includes monitoring for any adverse reactions to the chemical agent used. Patients may be advised to keep the treated area clean and dry, and to avoid any activities that could irritate the area, such as sexual intercourse, until healing is complete. The physician may schedule a follow-up appointment to assess the treatment's effectiveness and to ensure that the lesions have been adequately destroyed. Any remaining lesions or new growths may require additional treatment, which will be determined based on the patient's individual response to the procedure.

Short Descr DESTRUCTION PENIS LESION(S)
Medium Descr DSTRJ LESION PENIS SIMPLE CHEMICAL
Long Descr Destruction of lesion(s), penis (eg, condyloma, papilloma, molluscum contagiosum, herpetic vesicle), simple; chemical
Status Code Active Code
Global Days 010 - Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator STV-Packaged Codes
ASC Payment Indicator Packaged service/item; no separate payment made.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P6C - Minor procedures - other (Medicare fee schedule)
MUE 1
CCS Clinical Classification 117 - Other non-OR therapeutic procedures, male genital
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
AG Primary physician
GC This service has been performed in part by a resident under the direction of a teaching physician
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
Date
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Notes
2011-01-01 Changed Short description changed.
Pre-1990 Added Code added.
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