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Official Description

Excision of lesion, cornea (keratectomy, lamellar, partial), except pterygium

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 65400 refers to the excision of a lesion from the cornea, specifically a lamellar keratectomy that is partial in nature and excludes pterygium. Corneal lesions that necessitate excision can arise from various conditions, including dystrophic changes, degenerative processes, hypertrophic growths, or scar tissue formation. The procedure is typically performed under magnification using a slit lamp or an operating microscope, which allows for precise visualization of the lesion. During the excision, the surface epithelial cells of the cornea are carefully removed using instruments such as blunt forceps, spatulas, or sponges. This step is crucial as it helps to clearly define the margins of the lesion and exposes the underlying corneal epithelium along with any subepithelial fibrous or fibrovascular tissue that may be present. Following the delineation of the lesion, the deeper portions are excised through either blunt or sharp dissection techniques. To enhance the healing process, the surface of the cornea may be polished with a diamond burr, and a bandage contact lens is placed at the end of the procedure. This lens serves to protect the cornea and promote the regeneration of epithelial cells from the limbic stem cells, facilitating optimal recovery.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The excision of corneal lesions via CPT® Code 65400 is indicated for various conditions that affect the cornea. These indications include:

  • Dystrophic lesions - These are abnormalities in the cornea that can lead to visual impairment and may require surgical intervention.
  • Degenerative lesions - These lesions result from the gradual deterioration of corneal tissue, necessitating excision to restore corneal integrity and function.
  • Hypertrophic lesions - These are characterized by an abnormal increase in corneal tissue, which may obstruct vision and require removal.
  • Scar tissue - Scarring on the cornea can result from previous injuries or infections, and excision may be necessary to improve visual clarity.

2. Procedure

The procedure for excising a corneal lesion using CPT® Code 65400 involves several critical steps:

  • Visualization of the lesion - The surgeon begins by using a slit lamp or operating microscope to closely examine the corneal lesion. This magnification is essential for accurately assessing the size and extent of the lesion.
  • Debridement of surface epithelial cells - Once the lesion is visualized, the surgeon gently removes the surface epithelial cells from the cornea. This is accomplished using instruments such as blunt forceps, spatulas, or sponges, which help to delineate the margins of the lesion and expose the deeper layers of the cornea.
  • Dissection of the deeper lesion - After the margins are defined, the surgeon proceeds with the excision of the deeper portions of the lesion. This can be performed using either blunt or sharp dissection techniques, depending on the nature of the lesion and the surgeon's preference.
  • Polishing the corneal surface - Following the excision, the surface of the cornea may be polished using a diamond burr. This step is important for smoothing the corneal surface and promoting optimal healing.
  • Insertion of a bandage contact lens - At the conclusion of the procedure, a bandage contact lens is placed on the cornea. This lens serves to protect the cornea during the healing process and aids in the regeneration of corneal epithelial cells from the limbic stem cells.

3. Post-Procedure

After the excision of the corneal lesion, patients can expect specific post-procedure care and considerations. The bandage contact lens will remain in place for a designated period to facilitate healing and protect the cornea from external irritants. Patients may experience some discomfort or a foreign body sensation, which is typically managed with prescribed analgesics or topical medications. Follow-up appointments are essential to monitor the healing process and ensure that the cornea is regenerating properly. The healthcare provider will assess the corneal surface and may remove the bandage lens once adequate healing has occurred. Patients should be advised on signs of complications, such as increased pain, redness, or changes in vision, and instructed to contact their healthcare provider if these occur.

Short Descr REMOVAL OF EYE LESION
Medium Descr EXCISION LESION CORNEA XCP PTERYGIUM
Long Descr Excision of lesion, cornea (keratectomy, lamellar, partial), except pterygium
Status Code Active Code
Global Days 090 - Major Surgery
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 1 - 150% payment adjustment for bilateral procedures applies.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Procedure or Service, Multiple Reduction Applies
ASC Payment Indicator Surgical procedure on ASC list in CY 2007; payment based on OPPS relative payment weight.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P4E - Eye procedure - other
MUE 1
CCS Clinical Classification 19 - Other therapeutic procedures on eyelids, conjunctiva, cornea
RT Right side (used to identify procedures performed on the right side of the body)
LT Left side (used to identify procedures performed on the left side of the body)
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
SG Ambulatory surgical center (asc) facility service
50 Bilateral procedure: unless otherwise identified in the listings, bilateral procedures that are performed at the same session, should be identified by adding modifier 50 to the appropriate 5 digit code. note: this modifier should not be appended to designated "add-on" codes (see appendix d).
54 Surgical care only: when 1 physician or other qualified health care professional performs a surgical procedure and another provides preoperative and/or postoperative management, surgical services may be identified by adding modifier 54 to the usual procedure number.
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
55 Postoperative management only: when 1 physician or other qualified health care professional performed the postoperative management and another performed the surgical procedure, the postoperative component may be identified by adding modifier 55 to the usual procedure number.
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
74 Discontinued out-patient hospital/ambulatory surgery center (asc) procedure after administration of anesthesia: due to extenuating circumstances or those that threaten the well being of the patient, the physician may terminate a surgical or diagnostic procedure after the administration of anesthesia (local, regional block(s), general) or after the procedure was started (incision made, intubation started, scope inserted, etc). under these circumstances, the procedure started but terminated can be reported by its usual procedure number and the addition of modifier 74. note: the elective cancellation of a service prior to the administration of anesthesia and/or surgical preparation of the patient should not be reported. for physician reporting of a discontinued procedure, see modifier 53.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
CR Catastrophe/disaster related
E1 Upper left, eyelid
E2 Lower left, eyelid
ET Emergency services
GA Waiver of liability statement issued as required by payer policy, individual case
GC This service has been performed in part by a resident under the direction of a teaching physician
GW Service not related to the hospice patient's terminal condition
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
KX Requirements specified in the medical policy have been met
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
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