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Official Description

Iridectomy, with corneoscleral or corneal section; peripheral for glaucoma (separate procedure)

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 66625 is known as an iridectomy, specifically a peripheral iridectomy performed as a separate procedure to treat glaucoma. In this context, an iridectomy involves the surgical removal of a portion of the iris, which is the colored part of the eye. The primary goal of this procedure is to facilitate the drainage of aqueous humor, the fluid within the eye, from the anterior chamber to the posterior chamber. This drainage is crucial for reducing intraocular pressure (IOP), which is often elevated in patients suffering from glaucoma. Elevated IOP can lead to damage of the optic nerve and potential vision loss if not managed effectively. This procedure is particularly indicated for patients with angle-closure glaucoma, a condition where the drainage angle of the eye becomes blocked, leading to a rapid increase in IOP. When less invasive treatments, such as laser iridotomy, fail to achieve the desired reduction in IOP, a peripheral iridectomy may be necessary. During the procedure, a topical anesthetic is applied to ensure patient comfort. An incision is made in the cornea, typically at the limbus, which is the junction where the cornea meets the sclera. A small, full-thickness section of the iris is then excised. Unlike some surgical procedures, the corneal incision made during this process is generally not sutured, as it is expected to heal naturally. Post-operative care may include the application of antibiotic eye drops, and the use of a contact lens bandage or an eye patch to protect the eye during the healing process.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The procedure described by CPT® Code 66625 is indicated for specific conditions related to glaucoma. The following are the explicitly provided indications for performing a peripheral iridectomy:

  • Angle-Closure Glaucoma - This condition occurs when the drainage angle of the eye becomes obstructed, leading to a rapid increase in intraocular pressure (IOP). A peripheral iridectomy is performed when other treatments, such as laser iridotomy, are ineffective in reducing IOP.

2. Procedure

The procedural steps for performing a peripheral iridectomy under CPT® Code 66625 are as follows:

  • Step 1: Anesthesia Application - The procedure begins with the application of a topical anesthetic to the eye. This is crucial for ensuring that the patient remains comfortable and pain-free during the surgical intervention.
  • Step 2: Corneal Incision - A surgical incision is made in the cornea, typically at the limbus, which is the area where the cornea and sclera meet. This incision allows access to the iris for the subsequent excision.
  • Step 3: Iris Excision - A small, full-thickness section of the iris is excised. This step is critical as it creates an opening that facilitates the drainage of aqueous humor from the anterior chamber to the posterior chamber, thereby helping to lower IOP.
  • Step 4: Post-Incision Care - After the excision, the corneal incision is generally not closed with sutures, as it is expected to heal on its own. The surgeon may apply antibiotic drops to prevent infection and may also place a contact lens bandage or an eye patch over the eye to aid in the healing process.

3. Post-Procedure

Post-procedure care following a peripheral iridectomy includes monitoring for any signs of complications, such as infection or excessive bleeding. Patients are typically advised to use antibiotic eye drops as prescribed to minimize the risk of infection. The use of a contact lens bandage or an eye patch may be recommended to protect the eye during the initial healing phase. Patients should also be informed about the expected recovery process, which generally involves a gradual improvement in symptoms as intraocular pressure stabilizes. Follow-up appointments are essential to assess the healing process and to ensure that the desired reduction in IOP is achieved.

Short Descr REMOVAL OF IRIS
Medium Descr IRDEC CRNLSCLRL/CRNL SCTJ PRPH GLC SPX
Long Descr Iridectomy, with corneoscleral or corneal section; peripheral for glaucoma (separate procedure)
Status Code Active Code
Global Days 090 - Major Surgery
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 1 - 150% payment adjustment for bilateral procedures applies.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Hospital Part B services paid through a comprehensive APC
ASC Payment Indicator Surgical procedure on ASC list in CY 2007; payment based on OPPS relative payment weight.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P4E - Eye procedure - other
MUE 1
CCS Clinical Classification 20 - Other intraocular therapeutic procedures
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
LT Left side (used to identify procedures performed on the left side of the body)
RT Right side (used to identify procedures performed on the right side of the body)
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
SG Ambulatory surgical center (asc) facility service
50 Bilateral procedure: unless otherwise identified in the listings, bilateral procedures that are performed at the same session, should be identified by adding modifier 50 to the appropriate 5 digit code. note: this modifier should not be appended to designated "add-on" codes (see appendix d).
54 Surgical care only: when 1 physician or other qualified health care professional performs a surgical procedure and another provides preoperative and/or postoperative management, surgical services may be identified by adding modifier 54 to the usual procedure number.
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
80 Assistant surgeon: surgical assistant services may be identified by adding modifier 80 to the usual procedure number(s).
82 Assistant surgeon (when qualified resident surgeon not available): the unavailability of a qualified resident surgeon is a prerequisite for use of modifier 82 appended to the usual procedure code number(s).
AS Physician assistant, nurse practitioner, or clinical nurse specialist services for assistant at surgery
GC This service has been performed in part by a resident under the direction of a teaching physician
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GW Service not related to the hospice patient's terminal condition
X3 Episodic/broad services: for reporting services by clinicians who have broad responsibility for the comprehensive needs of the patient that is limited to a defined period and circumstance such as a hospitalization; reporting clinician service examples include but are not limited to the hospitalist's services rendered providing comprehensive and general care to a patient while admitted to the hospital
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
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