Coding Ahead
CasePilot
Medical Coding Assistant
CaseConsultant
Instant Email Coding Consultant
Case2Code
Search and Code Lookup Tool
CareerCenter
Medical Coding Job Board
Log in Register free account

Need help choosing the right code?

Ask CasePilot about procedures, modifiers, bundling, and coding guidance.

Try CasePilot

Official Description

Automated quantification and characterization of coronary atherosclerotic plaque to assess severity of coronary disease, using data from coronary computed tomographic angiography; data preparation and transmission, computerized analysis of data, with review of computerized analysis output to reconcile discordant data, interpretation and report

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 0623T refers to a comprehensive procedure for the automated quantification and characterization of coronary atherosclerotic plaque, which is essential for assessing the severity of coronary artery disease. Atherosclerotic plaque consists of various components that accumulate within the vessel intima, leading to the formation of lesions. These lesions can include blood cells, macrophages, lipids, smooth muscle cells, necrotic cellular debris, collagen, and calcium. The quantification and characterization of these plaques are critical, as they provide insights into the risk of plaque rupture and the potential for ischemic strokes, which may not be fully understood by merely measuring the size and margins of the lesions. The procedure utilizes advanced imaging techniques, specifically coronary computed tomographic angiography (CTA), to analyze the extent of calcification and the presence of different plaque types, such as necrotic cores or lipid-rich versus fibrous lesions. The automated analysis process involves sophisticated software that segments vessel margins and differentiates plaque components based on varying attenuation thresholds. This software also generates color maps to visually represent the different components of the plaque, enhancing the understanding of its characteristics. Automated quantitative histogram analysis further aids in the characterization of plaque by evaluating attenuation values in increments, which allows for a more detailed assessment. This method is notably faster than traditional manual techniques and is most effective for vessels larger than 2mm in diameter. For billing purposes, it is important to note that separate codes exist for specific parts of the process: code 0624T is used for data preparation and transmission, 0625T for the computerized analysis of the transmitted data, and 0626T for the review of the computerized analysis output. However, code 0623T encompasses the entire process, from data preparation to final reporting.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The procedure associated with CPT® Code 0623T is indicated for the assessment of coronary artery disease severity through the analysis of coronary atherosclerotic plaque. The following conditions may warrant this procedure:

  • Coronary Artery Disease (CAD) - Patients with known or suspected CAD may require evaluation of plaque characteristics to determine the risk of adverse cardiovascular events.
  • Assessment of Plaque Stability - Individuals with a history of ischemic events or those at high risk for plaque rupture may benefit from detailed plaque characterization.
  • Evaluation of Atherosclerotic Lesions - Patients presenting with symptoms suggestive of coronary artery obstruction may need quantification of plaque to guide treatment decisions.

2. Procedure

The procedure for CPT® Code 0623T involves several key steps that ensure a thorough analysis of coronary atherosclerotic plaque:

  • Data Preparation and Transmission - Initially, data is prepared from a coronary computed tomographic angiography (CTA) study. This involves the extraction of relevant imaging data, which is then transmitted to specialized software for analysis.
  • Computerized Analysis of Data - The transmitted data undergoes computerized analysis where the software automatically segments the vessel margins and differentiates the various components of the plaque based on attenuation thresholds. This step is crucial for accurately identifying the characteristics of the plaque.
  • Review of Computerized Analysis Output - After the analysis, a review of the computerized output is conducted to reconcile any discordant data. This ensures that the findings are consistent and reliable, which is essential for accurate interpretation.
  • Interpretation and Reporting - Finally, the results of the analysis are interpreted, and a comprehensive report is generated. This report includes detailed information about the severity of coronary disease based on the characteristics of the atherosclerotic plaque.

3. Post-Procedure

Post-procedure care following the automated quantification and characterization of coronary atherosclerotic plaque typically involves monitoring the patient for any immediate reactions to the imaging process. Patients may be advised to follow up with their healthcare provider to discuss the results of the analysis and any necessary treatment plans based on the findings. It is also important for healthcare professionals to ensure that the report generated from the procedure is integrated into the patient's medical record for ongoing management of coronary artery disease.

Short Descr AUTO QUANTIFICATION C PLAQUE
Medium Descr AUTO QUAN&CHARAC CORONARY ATHEROSCLEROTIC PLAQUE
Long Descr Automated quantification and characterization of coronary atherosclerotic plaque to assess severity of coronary disease, using data from coronary computed tomographic angiography; data preparation and transmission, computerized analysis of data, with review of computerized analysis output to reconcile discordant data, interpretation and report
Status Code Carriers Price the Code
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 4 - Global Test Only Code
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Items and Services Not Billable to the MAC
Berenson-Eggers TOS (BETOS) none
MUE 1
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
X5 Diagnostic services requested by another clinician: for reporting services by a clinician who furnishes care to the patient only as requested by another clinician or subsequent and related services requested by another clinician; this modifier is reported for patient relationships that may not be adequately captured by the above alternative categories; reporting clinician service examples include but are not limited to, the radiologist's interpretation of an imaging study requested by another clinician
XE Separate encounter, a service that is distinct because it occurred during a separate encounter
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
GA Waiver of liability statement issued as required by payer policy, individual case
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
Date
Action
Notes
2021-01-01 Added Code added.
Code
Description
Code
Description
CasePilot

Get instant expert-level medical coding assistance.

Ask about:
CPT Codes Guidelines Modifiers Crosswalks NCCI Edits Compliance Medicare Coverage
Example: "What is CPT code 99213?" or "Guidelines for E/M services"