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Official Description

Automated quantification and characterization of coronary atherosclerotic plaque to assess severity of coronary disease, using data from coronary computed tomographic angiography; data preparation and transmission

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 0624T refers to the automated quantification and characterization of coronary atherosclerotic plaque, which is a critical procedure for assessing the severity of coronary artery disease. Atherosclerotic plaque is formed by the accumulation of various constituents that thicken the intima of blood vessels, leading to the formation of lesions. These lesions can consist of blood cells, macrophages, lipids, smooth muscle cells, necrotic cellular debris, collagen, and calcium. The composition of these plaques can vary significantly, which is why quantifying and characterizing them is essential. This process involves assessing factors such as the extent of calcification, the presence of a necrotic core, and the differentiation between lipid-rich and fibrous lesions. Such detailed analysis is crucial as it can provide insights into the risk of plaque rupture and the potential for ischemic strokes, which may not be evident from merely measuring the size and margins of the lesions. The assessment of plaque characteristics and disease severity is performed using advanced image processing and reconstruction techniques derived from coronary computed tomographic angiography (CTA) studies. Various software solutions from different vendors are employed to automatically segment the vessel margins and differentiate the various components of the plaque based on specific attenuation threshold settings. Additionally, these software tools offer color mapping of the plaque components, enhancing the visualization and understanding of the plaque's characteristics. Automated quantitative histogram analysis of plaque attenuation values further aids in the characterization of the plaque. This automated approach is notably more efficient than manual techniques and is particularly effective for vessels larger than 2mm in diameter. It is important to note that CPT® Code 0624T specifically pertains to the data preparation and transmission phase of this process, while other codes, such as 0625T and 0626T, relate to subsequent analysis and interpretation stages.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The procedure associated with CPT® Code 0624T is indicated for the assessment of coronary artery disease through the evaluation of coronary atherosclerotic plaque. The following conditions and symptoms may warrant this procedure:

  • Coronary Artery Disease (CAD) - Patients with a diagnosis of CAD may require this assessment to evaluate the severity and characteristics of atherosclerotic plaques.
  • Risk of Ischemic Events - Individuals at higher risk for ischemic strokes or myocardial infarction due to plaque instability may benefit from this detailed analysis.
  • Assessment of Plaque Composition - Patients needing a comprehensive understanding of plaque composition, including the presence of calcified versus non-calcified lesions, may be indicated for this procedure.

2. Procedure

The procedure for CPT® Code 0624T involves several key steps that ensure accurate quantification and characterization of coronary atherosclerotic plaque:

  • Data Preparation - Initially, data from a coronary computed tomographic angiography (CTA) study is prepared for analysis. This involves organizing the imaging data to facilitate effective processing.
  • Data Transmission - Once the data is prepared, it is transmitted to specialized software designed for the automated analysis of coronary atherosclerotic plaque. This step is crucial for ensuring that the data is accurately processed and analyzed.
  • Automated Segmentation - The software automatically segments the vessel margins and differentiates the various components of the plaque using specific attenuation threshold settings. This segmentation is essential for identifying the different constituents of the plaque.
  • Color Mapping - The software provides a color mapping of the plaque components, which enhances visualization and aids in the interpretation of the plaque's characteristics.
  • Quantitative Histogram Analysis - An automated quantitative histogram analysis of plaque attenuation values is performed, which increases the accuracy of plaque characterization and helps in assessing the risk associated with the plaque.

3. Post-Procedure

After the completion of the data preparation and transmission process associated with CPT® Code 0624T, the next steps typically involve further analysis and interpretation of the transmitted data. It is important to note that while this code covers the initial data handling, subsequent codes such as 0625T and 0626T are used for the computer analysis of the transmitted data and the review of the computerized analysis output, respectively. The results from these analyses will contribute to the overall assessment of coronary artery disease and guide further clinical decision-making. Patients may be monitored for any immediate reactions to the imaging process, and follow-up appointments may be scheduled to discuss the findings and potential treatment options based on the analysis results.

Short Descr AUTO QUAN C PLAQ DATA PREP
Medium Descr AUTO QUAN&CHARAC CORONARY PLAQ DATA PREP&TRNSMIS
Long Descr Automated quantification and characterization of coronary atherosclerotic plaque to assess severity of coronary disease, using data from coronary computed tomographic angiography; data preparation and transmission
Status Code Carriers Price the Code
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 3 - Technical Component Only Code
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Items and Services Packaged into APC Rates
Berenson-Eggers TOS (BETOS) none
MUE 1
Date
Action
Notes
2021-01-01 Added Code added.
Code
Description
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