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Official Description

Endoscopic retrograde cholangiopancreatography (ERCP); diagnostic, including collection of specimen(s) by brushing or washing, when performed (separate procedure)

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

Endoscopic retrograde cholangiopancreatography (ERCP) is a diagnostic procedure that utilizes an endoscope to examine the pancreatic and biliary ducts, which are responsible for draining the pancreas, liver, and gallbladder. This procedure is particularly focused on identifying issues within the bile ducts, which can include a variety of conditions affecting the liver, gallbladder, and pancreas. During an ERCP, the physician passes an endoscope through the patient's esophagus and stomach, advancing it into the duodenum, where the pancreatic duct and common bile duct converge at a location known as the ampulla of Vater, located at the major duodenal papilla. Once the endoscope is in place, a smaller catheter is introduced through the scope to cannulate the ampulla of Vater. Following this, contrast dye is injected into the ducts, allowing for visualization of the common bile duct, biliary tract, gallbladder, and pancreas via X-ray imaging. This imaging is crucial for detecting potential abnormalities such as gallstones, strictures, leaks, scarring, or malignancies. Additionally, the procedure may involve the advancement of the catheter over a guidewire into the common duct, biliary tract, gallbladder, and/or pancreas to facilitate the collection of cellular specimens through brushing or washing techniques. It is important to note that if tissue samples (biopsies) are obtained during the procedure, the appropriate code to use is 43261.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

Endoscopic retrograde cholangiopancreatography (ERCP) is indicated for a variety of conditions affecting the biliary and pancreatic systems. The following are the primary indications for performing this diagnostic procedure:

  • Gallstones - Presence of gallstones in the bile ducts that may cause obstruction or inflammation.
  • Strictures - Narrowing of the bile ducts that can lead to bile flow obstruction.
  • Leaks - Detection of bile leaks that may occur due to trauma, surgery, or other pathological conditions.
  • Scarring - Identification of scarring in the bile ducts that may affect normal function.
  • Cancer - Evaluation for malignancies in the pancreas, bile ducts, or gallbladder.

2. Procedure

The procedure of endoscopic retrograde cholangiopancreatography (ERCP) involves several critical steps to ensure accurate diagnosis and specimen collection. The following outlines the procedural steps:

  • Step 1: Patient Preparation - The patient is typically required to fast for several hours prior to the procedure to ensure an empty stomach. Sedation is administered to help the patient relax and minimize discomfort during the procedure.
  • Step 2: Endoscope Insertion - The physician carefully inserts the endoscope through the patient's mouth, guiding it through the esophagus and stomach, and into the duodenum. This step requires precision to avoid injury to surrounding tissues.
  • Step 3: Cannulation of the Ampulla of Vater - Once the endoscope reaches the duodenum, the physician locates the ampulla of Vater, where the pancreatic duct and common bile duct converge. A smaller catheter is then passed through the endoscope to cannulate this area.
  • Step 4: Contrast Dye Injection - After successful cannulation, contrast dye is injected into the ducts through the catheter. This allows for the visualization of the biliary and pancreatic systems on X-ray imaging.
  • Step 5: Imaging and Evaluation - X-ray images are taken immediately after the dye injection to assess the anatomy and identify any abnormalities such as gallstones, strictures, or tumors.
  • Step 6: Specimen Collection - If necessary, the catheter may be advanced over a guidewire into the common duct, biliary tract, gallbladder, and/or pancreas to collect cellular specimens. This can be done through brushing or washing techniques to obtain samples for further analysis.

3. Post-Procedure

After the completion of the ERCP, the patient is monitored in a recovery area until the effects of sedation wear off. It is common for patients to experience some throat discomfort due to the endoscope insertion. Patients may also be advised to refrain from eating or drinking for a short period until they are fully alert and able to swallow safely. Depending on the findings during the procedure, further treatment may be necessary, which could include additional procedures or surgical interventions. Patients are typically provided with specific post-procedure instructions, including signs of complications to watch for, such as abdominal pain, fever, or jaundice, and are advised to follow up with their healthcare provider for any necessary follow-up care or additional testing.

Short Descr ERCP W/SPECIMEN COLLECTION
Medium Descr ERCP DX COLLECTION SPECIMEN BRUSHING/WASHING
Long Descr Endoscopic retrograde cholangiopancreatography (ERCP); diagnostic, including collection of specimen(s) by brushing or washing, when performed (separate procedure)
Status Code Active Code
Global Days 000 - Endoscopic or Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Hospital Part B services paid through a comprehensive APC
ASC Payment Indicator Surgical procedure on ASC list in CY 2007; payment based on OPPS relative payment weight.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P8B - Endoscopy - upper gastrointestinal
MUE 1
CCS Clinical Classification 82 - Endoscopic retrograde cannulation of pancreas (ERCP)

This is a primary code that can be used with these additional add-on codes.

0397T Addon Code MPFS Status: Carrier Priced APC N ASC N1 Endoscopic retrograde cholangiopancreatography (ERCP), with optical endomicroscopy (List separately in addition to code for primary procedure)
43273 Addon Code MPFS Status: Active Code APC N ASC N1 CPT Assistant Article Illustration for Code Endoscopic cannulation of papilla with direct visualization of pancreatic/common bile duct(s) (List separately in addition to code(s) for primary procedure)
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
52 Reduced services: under certain circumstances a service or procedure is partially reduced or eliminated at the discretion of the physician or other qualified health care professional. under these circumstances the service provided can be identified by its usual procedure number and the addition of modifier 52, signifying that the service is reduced. this provides a means of reporting reduced services without disturbing the identification of the basic service. note: for hospital outpatient reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well-being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
22 Increased procedural services: when the work required to provide a service is substantially greater than typically required, it may be identified by adding modifier 22 to the usual procedure code. documentation must support the substantial additional work and the reason for the additional work (ie, increased intensity, time, technical difficulty of procedure, severity of patient's condition, physical and mental effort required). note: this modifier should not be appended to an e/m service.
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
73 Discontinued out-patient hospital/ambulatory surgery center (asc) procedure prior to the administration of anesthesia: due to extenuating circumstances or those that threaten the well being of the patient, the physician may cancel a surgical or diagnostic procedure subsequent to the patient's surgical preparation (including sedation when provided, and being taken to the room where the procedure is to be performed), but prior to the administration of anesthesia (local, regional block(s) or general). under these circumstances, the intended service that is prepared for but cancelled can be reported by its usual procedure number and the addition of modifier 73. note: the elective cancellation of a service prior to the administration of anesthesia and/or surgical preparation of the patient should not be reported. for physician reporting of a discontinued procedure, see modifier 53.
74 Discontinued out-patient hospital/ambulatory surgery center (asc) procedure after administration of anesthesia: due to extenuating circumstances or those that threaten the well being of the patient, the physician may terminate a surgical or diagnostic procedure after the administration of anesthesia (local, regional block(s), general) or after the procedure was started (incision made, intubation started, scope inserted, etc). under these circumstances, the procedure started but terminated can be reported by its usual procedure number and the addition of modifier 74. note: the elective cancellation of a service prior to the administration of anesthesia and/or surgical preparation of the patient should not be reported. for physician reporting of a discontinued procedure, see modifier 53.
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
80 Assistant surgeon: surgical assistant services may be identified by adding modifier 80 to the usual procedure number(s).
82 Assistant surgeon (when qualified resident surgeon not available): the unavailability of a qualified resident surgeon is a prerequisite for use of modifier 82 appended to the usual procedure code number(s).
AG Primary physician
AS Physician assistant, nurse practitioner, or clinical nurse specialist services for assistant at surgery
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
CR Catastrophe/disaster related
GC This service has been performed in part by a resident under the direction of a teaching physician
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GW Service not related to the hospice patient's terminal condition
GZ Item or service expected to be denied as not reasonable and necessary
PT Colorectal cancer screening test; converted to diagnostic test or other procedure
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
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2017-01-01 Changed Moderate (Conscious) Sedation flag removed. See new Moderate Sedation category.
2014-01-01 Changed Description Changed
2002-01-01 Changed Code description changed.
Pre-1990 Added Code added.
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