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Official Description

Removal of corneal epithelium; with application of chelating agent (eg, EDTA)

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 65436 involves the removal of the corneal epithelium, which is the outermost layer of the cornea, a transparent front part of the eye. This procedure is typically indicated for patients with conditions that have led to the deterioration or damage of the corneal epithelium, such as disease, erosion, or dystrophy. The removal process can be performed using various techniques, including abrasion or curettage, which involve scraping or brushing away the epithelial layer. The goal of this procedure is to eliminate unhealthy or compromised epithelial tissue to promote healing and restore corneal integrity. Following the removal of the epithelium, a chelating agent, such as ethylenediaminetetraacetic acid (EDTA), is applied to the exposed underlying tissue. This chemical application serves to cauterize the area and may assist in the removal of any calcifications or deposits that may have formed on the Bowman's layer, which lies beneath the epithelium. The procedure is performed with precision, utilizing instruments such as sponges or blades for the epithelial removal and surgical sponges or specialized reservoirs for the application of the chelating agent.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The procedure described by CPT® Code 65436 is indicated for the following conditions:

  • Diseased Corneal Epithelium - The procedure is performed to address areas of the corneal epithelium that are affected by disease, which may compromise vision and overall eye health.
  • Eroded Corneal Epithelium - This procedure is indicated for patients with erosion of the corneal epithelium, where the protective layer has been damaged, leading to potential complications.
  • Damaged Corneal Epithelium - The removal of damaged epithelial tissue is necessary to facilitate healing and restore the cornea's normal function.
  • Dystrophied Corneal Epithelium - In cases of epithelial dystrophy, where the corneal epithelium is abnormally developed or functioning, this procedure can help remove the affected tissue.

2. Procedure

The procedure for CPT® Code 65436 involves several key steps that ensure the effective removal of the corneal epithelium and the application of a chelating agent:

  • Step 1: Preparation - The patient is positioned comfortably, and the eye is prepared for the procedure. Anesthesia may be administered to minimize discomfort during the removal of the corneal epithelium.
  • Step 2: Removal of Corneal Epithelium - The physician uses a brushing or scraping instrument, such as a sponge or blade, to carefully remove the corneal epithelium. This step involves separating the soft epithelial layer from the underlying Bowman's layer, ensuring that the removal is thorough yet precise.
  • Step 3: Application of Chelating Agent - After the epithelium has been removed, a chelating agent, such as EDTA, is applied to the newly exposed tissue. This is typically done using surgical sponges or a reservoir, such as a corneal trephine or well, to ensure even distribution of the agent.
  • Step 4: Additional Scraping (if necessary) - Following the application of the chelating agent, additional scraping may be performed to remove any calcifications or deposits that may be present on the Bowman's layer. This step is crucial for ensuring that the underlying tissue is clean and free from obstructions that could impede healing.

3. Post-Procedure

After the completion of the procedure, the patient may be monitored for any immediate complications. Post-procedure care typically includes instructions for eye care, which may involve the use of antibiotic or anti-inflammatory eye drops to prevent infection and reduce inflammation. Patients are advised to avoid rubbing their eyes and to follow up with their healthcare provider for further evaluation and monitoring of the healing process. The expected recovery time may vary depending on the individual’s condition and the extent of the procedure performed.

Short Descr CURETTE/TREAT CORNEA
Medium Descr RMVL CORNEAL EPITHELIUM W/APPL CHELATING AGENT
Long Descr Removal of corneal epithelium; with application of chelating agent (eg, EDTA)
Status Code Active Code
Global Days 090 - Major Surgery
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 1 - 150% payment adjustment for bilateral procedures applies.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Hospital Part B services paid through a comprehensive APC
ASC Payment Indicator Office-based surgical procedure added to ASC list in CY 2008 or later with MPFS nonfacility PE RVUs; payment based on MPFS nonfacility PE RVUs.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P6C - Minor procedures - other (Medicare fee schedule)
MUE 1
CCS Clinical Classification 19 - Other therapeutic procedures on eyelids, conjunctiva, cornea
RT Right side (used to identify procedures performed on the right side of the body)
LT Left side (used to identify procedures performed on the left side of the body)
50 Bilateral procedure: unless otherwise identified in the listings, bilateral procedures that are performed at the same session, should be identified by adding modifier 50 to the appropriate 5 digit code. note: this modifier should not be appended to designated "add-on" codes (see appendix d).
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
54 Surgical care only: when 1 physician or other qualified health care professional performs a surgical procedure and another provides preoperative and/or postoperative management, surgical services may be identified by adding modifier 54 to the usual procedure number.
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
CR Catastrophe/disaster related
GC This service has been performed in part by a resident under the direction of a teaching physician
GW Service not related to the hospice patient's terminal condition
SG Ambulatory surgical center (asc) facility service
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