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Official Description

Biopsy of lacrimal gland

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 68510 refers to a biopsy of the lacrimal gland, which is a small gland located in the upper outer region of the eye responsible for producing tears. This procedure is typically performed to obtain tissue samples from the lacrimal gland for diagnostic purposes, particularly to investigate potential abnormalities or diseases affecting the gland. The process begins with the cleansing of the skin over the eye to minimize the risk of infection. A local anesthetic is then administered to ensure the patient experiences minimal discomfort during the procedure. An incision is made on the temporal aspect of the eye, allowing access to the underlying structures. The temporal muscle is carefully exposed and retracted laterally, which facilitates visibility and access to the lacrimal gland. Once the gland is adequately exposed, it is inspected for any signs of disease or abnormality. Tissue samples are then collected from the lacrimal gland, which are crucial for further pathological examination in a laboratory setting. This examination can help in diagnosing conditions such as inflammation, tumors, or other pathologies affecting the lacrimal gland. After the biopsy is completed, the operative wound is meticulously closed in layers to promote proper healing and minimize scarring.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The biopsy of the lacrimal gland, as indicated by CPT® Code 68510, is performed for several specific reasons related to the assessment of the gland's health. The following conditions may warrant this procedure:

  • Suspicion of Tumors The procedure is indicated when there is a clinical suspicion of neoplastic growths within the lacrimal gland, which may require histological evaluation to determine the nature of the tumor.
  • Chronic Inflammation A biopsy may be necessary in cases of chronic inflammation of the lacrimal gland, where the underlying cause needs to be identified to guide treatment.
  • Autoimmune Disorders Conditions such as Sjögren's syndrome or other autoimmune disorders that may affect the lacrimal gland can also necessitate a biopsy to assess the extent of gland involvement.
  • Unexplained Lacrimal Gland Enlargement If there is unexplained swelling or enlargement of the lacrimal gland, a biopsy can help determine the cause and appropriate management.

2. Procedure

The procedure for a biopsy of the lacrimal gland involves several critical steps to ensure accurate tissue sampling and patient safety. The following outlines the procedural steps:

  • Step 1: Skin Preparation The first step involves cleansing the skin over the eye to reduce the risk of infection. This is a crucial preparatory measure that ensures a sterile environment for the procedure.
  • Step 2: Anesthesia Administration Following skin preparation, a local anesthetic is injected to numb the area around the eye. This step is essential for minimizing discomfort during the procedure, allowing the patient to remain comfortable while the biopsy is performed.
  • Step 3: Incision An incision is then made over the temporal aspect of the eye. This strategic location is chosen to provide optimal access to the lacrimal gland while minimizing potential complications.
  • Step 4: Exposure of the Temporal Muscle Once the incision is made, the temporal muscle is carefully exposed and retracted laterally. This retraction is necessary to gain clear visibility and access to the lacrimal gland, which lies beneath the muscle.
  • Step 5: Inspection of the Lacrimal Gland With the lacrimal gland now exposed, the surgeon inspects it for any abnormalities. This visual examination is critical for identifying any pathological changes that may be present.
  • Step 6: Tissue Sampling One or more tissue samples are then obtained from the lacrimal gland. These samples are vital for subsequent pathological examination, which will provide insights into the gland's health and any underlying conditions.
  • Step 7: Wound Closure After the tissue samples are collected, the operative wound is closed in layers. This layered closure technique is important for promoting optimal healing and minimizing scarring at the incision site.

3. Post-Procedure

After the biopsy of the lacrimal gland is completed, patients may be monitored for any immediate complications, such as bleeding or infection. Post-procedure care typically includes instructions for wound care to ensure proper healing. Patients may be advised to avoid strenuous activities and to keep the area clean and dry. Follow-up appointments may be scheduled to discuss the results of the pathology examination and to determine any further management based on the findings. It is also important for patients to report any unusual symptoms, such as increased pain, swelling, or discharge from the incision site, to their healthcare provider promptly.

Short Descr BIOPSY OF TEAR GLAND
Medium Descr BIOPSY LACRIMAL GLAND
Long Descr Biopsy of lacrimal gland
Status Code Active Code
Global Days 000 - Endoscopic or Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 1 - 150% payment adjustment for bilateral procedures applies.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Hospital Part B services paid through a comprehensive APC
ASC Payment Indicator Surgical procedure on ASC list in CY 2007; payment based on OPPS relative payment weight.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P4E - Eye procedure - other
MUE 1
CCS Clinical Classification 18 - Diagnostic procedures on eye
50 Bilateral procedure: unless otherwise identified in the listings, bilateral procedures that are performed at the same session, should be identified by adding modifier 50 to the appropriate 5 digit code. note: this modifier should not be appended to designated "add-on" codes (see appendix d).
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
82 Assistant surgeon (when qualified resident surgeon not available): the unavailability of a qualified resident surgeon is a prerequisite for use of modifier 82 appended to the usual procedure code number(s).
E3 Upper right, eyelid
GC This service has been performed in part by a resident under the direction of a teaching physician
LT Left side (used to identify procedures performed on the left side of the body)
RT Right side (used to identify procedures performed on the right side of the body)
SG Ambulatory surgical center (asc) facility service
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