Coding Ahead
CasePilot
Medical Coding Assistant
CaseConsultant
Instant Email Coding Consultant
Case2Code
Search and Code Lookup Tool
CareerCenter
Medical Coding Job Board
Log in Register free account

Need help choosing the right code?

Ask CasePilot about procedures, modifiers, bundling, and coding guidance.

Try CasePilot

Official Description

Biopsy of lacrimal sac

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 68525 refers to a biopsy of the lacrimal sac, which is a critical component of the tear drainage system located in the inner corner of the eye. This procedure involves a careful and methodical approach to access the lacrimal sac, which is responsible for collecting tears from the eye and draining them into the nasal cavity. The process begins with the cleansing of the skin surrounding the eye to minimize the risk of infection. A local anesthetic is then administered subcutaneously, ensuring that the patient experiences minimal discomfort during the procedure. An incision is made on the inner aspect of the lower eyelid, allowing the surgeon to expose the lacrimal sac, nasolacrimal duct, and canaliculi, which are the small channels that carry tears. Once these structures are visible, the surgeon inspects them for any abnormalities. The next step involves obtaining one or two tissue samples from the lacrimal sac, which are crucial for pathological examination to identify any potential diseases or conditions affecting the lacrimal system. After the biopsy is completed, the operative wound is meticulously closed in layers to promote proper healing and minimize scarring. This procedure is essential for diagnosing conditions related to the lacrimal system and ensuring appropriate treatment can be administered based on the findings from the pathology examination.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The biopsy of the lacrimal sac, as described by CPT® Code 68525, is indicated for several specific conditions and symptoms that may affect the lacrimal system. These indications include:

  • Suspected Tumors - When there is a suspicion of neoplastic growths within the lacrimal sac or surrounding structures, a biopsy is performed to obtain tissue samples for histological analysis.
  • Chronic Inflammation - In cases of persistent inflammation of the lacrimal sac, a biopsy may be necessary to determine the underlying cause and to rule out any malignancies.
  • Obstruction of the Nasolacrimal Duct - If there are signs of obstruction leading to recurrent infections or epiphora (excessive tearing), a biopsy can help assess the condition of the lacrimal sac.
  • Infectious Processes - In instances where there is a suspected infectious process affecting the lacrimal sac, obtaining tissue samples can aid in identifying the causative organism.

2. Procedure

The procedure for a biopsy of the lacrimal sac involves several critical steps to ensure accurate sampling and patient safety. The steps are as follows:

  • Step 1: Preparation - The skin around the eye is thoroughly cleansed to reduce the risk of infection. This step is crucial as it prepares the surgical site for the procedure.
  • Step 2: Anesthesia - A local anesthetic is injected subcutaneously around the lacrimal sac. This ensures that the patient remains comfortable and pain-free during the procedure.
  • Step 3: Incision - An incision is made over the inner aspect of the lower eyelid. This strategic location allows for optimal access to the lacrimal sac and associated structures.
  • Step 4: Exposure - The lacrimal sac, nasolacrimal duct, and canaliculi are carefully exposed. This step is essential for visual inspection and for obtaining tissue samples.
  • Step 5: Inspection - The surgeon inspects the lacrimal sac and surrounding structures for any abnormalities, which may indicate underlying pathology.
  • Step 6: Tissue Sampling - One or two tissue samples are obtained from the lacrimal sac. These samples are critical for further pathological examination to diagnose any potential conditions.
  • Step 7: Closure - After the biopsy is completed, the operative wound is closed in layers. This layered closure technique promotes optimal healing and minimizes scarring.

3. Post-Procedure

Following the biopsy of the lacrimal sac, patients can expect specific post-procedure care and considerations. It is important to monitor the surgical site for any signs of infection, such as increased redness, swelling, or discharge. Patients may be advised to apply cold compresses to the area to reduce swelling and discomfort. Pain management may be necessary, and over-the-counter analgesics can be recommended. Additionally, patients should be instructed to avoid strenuous activities and to keep the area clean and dry. Follow-up appointments may be scheduled to assess healing and to discuss the results of the pathology examination. Proper adherence to post-procedure instructions is essential for optimal recovery and to ensure the best possible outcomes.

Short Descr BIOPSY OF TEAR SAC
Medium Descr BIOPSY LACRIMAL SAC
Long Descr Biopsy of lacrimal sac
Status Code Active Code
Global Days 000 - Endoscopic or Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 1 - 150% payment adjustment for bilateral procedures applies.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 1 - Co-surgeons could be paid, though supporting documentation is required...
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Hospital Part B services paid through a comprehensive APC
ASC Payment Indicator Surgical procedure on ASC list in CY 2007; payment based on OPPS relative payment weight.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P6C - Minor procedures - other (Medicare fee schedule)
MUE 1
CCS Clinical Classification 18 - Diagnostic procedures on eye
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
LT Left side (used to identify procedures performed on the left side of the body)
22 Increased procedural services: when the work required to provide a service is substantially greater than typically required, it may be identified by adding modifier 22 to the usual procedure code. documentation must support the substantial additional work and the reason for the additional work (ie, increased intensity, time, technical difficulty of procedure, severity of patient's condition, physical and mental effort required). note: this modifier should not be appended to an e/m service.
50 Bilateral procedure: unless otherwise identified in the listings, bilateral procedures that are performed at the same session, should be identified by adding modifier 50 to the appropriate 5 digit code. note: this modifier should not be appended to designated "add-on" codes (see appendix d).
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
80 Assistant surgeon: surgical assistant services may be identified by adding modifier 80 to the usual procedure number(s).
E1 Upper left, eyelid
E2 Lower left, eyelid
E4 Lower right, eyelid
GC This service has been performed in part by a resident under the direction of a teaching physician
GW Service not related to the hospice patient's terminal condition
RT Right side (used to identify procedures performed on the right side of the body)
SG Ambulatory surgical center (asc) facility service
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
Date
Action
Notes
Pre-1990 Added Code added.
Code
Description
Code
Description
Code
Description
Code
Description
Code
Description
CasePilot

Get instant expert-level medical coding assistance.

Ask about:
CPT Codes Guidelines Modifiers Crosswalks NCCI Edits Compliance Medicare Coverage
Example: "What is CPT code 99213?" or "Guidelines for E/M services"