How To Use CPT Code 0083U

CPT 0083U describes a proprietary laboratory analysis (PLA) code for the Onco4D™ test from Animated Dynamics, Inc. This test utilizes motility contrast tomography to determine the likelihood of sensitivity or resistance to chemotherapy drugs or drug combinations. In this article, we will explore the official description, procedure, qualifying circumstances, appropriate usage, documentation requirements, billing guidelines, historical information, and examples of CPT code 0083U.

1. What is CPT Code 0083U?

CPT 0083U is a proprietary laboratory analysis (PLA) code that applies to the Onco4D™ test developed by Animated Dynamics, Inc. This test utilizes motility contrast tomography to assess the response of cancer cells to chemotherapy drugs or drug combinations. By analyzing the motility contrast imaging (MCI) of fresh or frozen tissue samples, the Onco4D™ test provides valuable information about the likelihood of sensitivity or resistance to specific chemotherapy treatments.

2. Official Description

The official description of CPT code 0083U is: ‘Oncology, response to chemotherapy drugs using motility contrast tomography, fresh or frozen tissue, reported as likelihood of sensitivity or resistance to drugs or drug combinations.’

3. Procedure

  1. The technician collects fresh or frozen tissue samples from a biopsy.
  2. The tissue samples are placed in a multiwall plate.
  3. The samples are exposed to various chemotherapy drugs or drug combinations.
  4. LED light is shined into the middle of the tissue, and motility contrast imaging captures the scattered light.
  5. A 3D color image is created, indicating the responsiveness of the cancer cells to the tested drugs.

4. Qualifying circumstances

CPT code 0083U is applicable when the Onco4D™ test from Animated Dynamics, Inc. is performed using motility contrast tomography on fresh or frozen tissue samples. This test is specifically designed to assess the likelihood of sensitivity or resistance to chemotherapy drugs or drug combinations in oncology patients.

5. When to use CPT code 0083U

CPT code 0083U should be used when the Onco4D™ test is performed to evaluate the response of cancer cells to chemotherapy drugs or drug combinations. It is important to note that this code should only be reported for the Onco4D™ test and not for any other laboratory analyses. Additionally, only one unit of this code should be reported for a single specimen analyzed on a single date of service.

6. Documentation requirements

To support a claim for CPT code 0083U, the following documentation is required:

  • Identification of the patient and the specific tissue sample analyzed
  • Details of the motility contrast tomography procedure
  • Specific chemotherapy drugs or drug combinations tested
  • Results of the Onco4D™ test indicating the likelihood of sensitivity or resistance to the tested drugs
  • Date of service and the signature of the healthcare professional performing or supervising the test

7. Billing guidelines

When billing for CPT code 0083U, it is important to use this code only for the Onco4D™ test from Animated Dynamics, Inc. and not for any other laboratory analyses. This code takes precedence over other laboratory/pathology codes and should not be reported with any other CPT codes. Some payers may separately reimburse for the collection of the tissue specimen, so it is advisable to check with the appropriate payer for their specific guidelines.

8. Historical information

CPT code 0083U was added to the Current Procedural Terminology system on January 1, 2019. As of now, there have been no updates or changes to this code since its addition.

9. Examples

  1. A patient with ovarian cancer undergoes the Onco4D™ test to determine the likelihood of sensitivity or resistance to a specific chemotherapy drug.
  2. A tissue sample from a breast cancer biopsy is analyzed using the Onco4D™ test to assess the response to a combination of chemotherapy drugs.
  3. A bladder cancer patient’s tissue sample is tested with the Onco4D™ test to evaluate the likelihood of sensitivity or resistance to a particular chemotherapy drug.
  4. The Onco4D™ test is performed on a frozen tissue sample from a patient with esophageal cancer to determine the response to a combination of chemotherapy drugs.
  5. A healthcare professional orders the Onco4D™ test for a patient with breast cancer to guide the selection of chemotherapy treatments based on the likelihood of sensitivity or resistance.
  6. The Onco4D™ test is utilized to assess the response of a tissue sample from a patient with ovarian cancer to a specific chemotherapy drug combination.
  7. A patient with bladder cancer undergoes the Onco4D™ test to determine the likelihood of sensitivity or resistance to a particular chemotherapy drug.
  8. The Onco4D™ test is performed on a fresh tissue sample from a patient with esophageal cancer to evaluate the response to a specific chemotherapy drug.
  9. A healthcare professional orders the Onco4D™ test for a patient with breast cancer to guide the selection of chemotherapy treatments based on the likelihood of sensitivity or resistance.
  10. A tissue sample from a patient with ovarian cancer is analyzed using the Onco4D™ test to assess the response to a combination of chemotherapy drugs.

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