How To Use CPT Code 0084U

CPT 0084U describes the genotyping of 10 blood groups with phenotype prediction of 37 red blood cell antigens using the BLOODchip®ID CORE XT™ test from Grifols Diagnostic Solutions Inc. This article will cover the description, official description, procedure, qualifying circumstances, appropriate usage, documentation requirements, billing guidelines, historical information, and examples.

1. What is CPT Code 0084U?

CPT 0084U can be used to describe the genotyping of 10 blood groups with phenotype prediction of 37 red blood cell antigens. This code is specifically used for the BLOODchip®ID CORE XT™ test from Grifols Diagnostic Solutions Inc., which is a molecular-based assay that helps determine blood compatibility by identifying blood donor and recipient red blood cell antigen phenotypes.

2. Official Description

The official description of CPT code 0084U is: ‘Red blood cell antigen typing, DNA, genotyping of 10 blood groups with phenotype prediction of 37 red blood cell antigens.’

3. Procedure

1. The BLOODchip®ID CORE XT™ test uses a proprietary multiplexed molecular polymerase chain reaction (PCR) amplification assay of polymorphisms technology to identify the presence or absence of selected alleles associated with specific observable traits.
2. Color-coded microspheres with allele-specific probes hybridize specifically to the labeled PCR products, and the fluorescent labeling allows detection and quantification of the hybridization signal.
3. A separate proprietary imaging system captures the fluorescent signal from individual DNA strands, which is then compared to a library of phenotypes.
4. Software analyzes the raw data and generates assay results, predicting the phenotype of 37 red blood cell antigens based on the identified alleles.
5. The BLOODchip®ID CORE XT™ test analyzes a whole blood specimen for 10 blood groups (RhCE, Kell, Kidd, Duffy, MNS, Diego, Dombrock, Colton, Cartwright, and Lutheran) and predicts the phenotype of 37 red blood cell antigens.

4. Qualifying circumstances

CPT 0084U is used for patients who need repeated blood transfusions to ensure compatibility between the donor and recipient. It is particularly useful for patients who may develop antibodies to non-ABO antigens, such as Rh antigens, due to frequent transfusions. The test analyzes 10 blood groups and predicts the phenotype of 37 red blood cell antigens.

5. When to use CPT code 0084U

CPT code 0084U should be used when the BLOODchip®ID CORE XT™ test from Grifols Diagnostic Solutions Inc. is performed to genotype 10 blood groups and predict the phenotype of 37 red blood cell antigens. This code is specific to this test and should not be used for any other purpose.

6. Documentation requirements

To support a claim for CPT code 0084U, the documentation should include:

• Order for the BLOODchip®ID CORE XT™ test
• Results of the test indicating the genotyping of 10 blood groups and the predicted phenotype of 37 red blood cell antigens
• Date and time of the test
• Signature of the healthcare professional who ordered or performed the test

7. Billing guidelines

When billing for CPT code 0084U, ensure that the BLOODchip®ID CORE XT™ test from Grifols Diagnostic Solutions Inc. is performed. This code should not be reported with any other CPT code. It is important to check with the appropriate payer regarding any additional requirements or coverage policies for this specific test.

8. Historical information

CPT code 0084U is a Proprietary Laboratory Analyses (PLA) code that was added to the CPT code set to identify specific proprietary laboratory tests. It is a unique code for the BLOODchip®ID CORE XT™ test from Grifols Diagnostic Solutions Inc. There have been no updates to the code since its addition.

9. Examples

1. A patient with sickle cell anemia requiring frequent blood transfusions undergoes the BLOODchip®ID CORE XT™ test to determine blood compatibility and predict the phenotype of 37 red blood cell antigens.
2. A patient in need of a bone marrow transplant undergoes the BLOODchip®ID CORE XT™ test to identify compatible donors based on blood group genotyping and predicted antigen phenotypes.
3. A patient with a history of transfusion reactions undergoes the BLOODchip®ID CORE XT™ test to identify potential non-ABO antigen mismatches and ensure compatibility for future transfusions.
4. A patient with a rare blood type undergoes the BLOODchip®ID CORE XT™ test to determine the specific genotype and predict the phenotype of 37 red blood cell antigens.
5. A patient with multiple blood transfusions in the past undergoes the BLOODchip®ID CORE XT™ test to assess the risk of developing antibodies to non-ABO antigens and ensure compatibility for future transfusions.
6. A patient with a known blood group incompatibility undergoes the BLOODchip®ID CORE XT™ test to determine the specific genotype and predict the phenotype of 37 red blood cell antigens.
7. A patient with a rare red blood cell antigen phenotype undergoes the BLOODchip®ID CORE XT™ test to confirm the presence of specific alleles and ensure accurate blood typing.
8. A patient with a history of transfusion reactions undergoes the BLOODchip®ID CORE XT™ test to identify potential non-ABO antigen mismatches and ensure compatibility for future transfusions.
9. A patient with a rare blood type undergoes the BLOODchip®ID CORE XT™ test to determine the specific genotype and predict the phenotype of 37 red blood cell antigens.
10. A patient with multiple blood transfusions in the past undergoes the BLOODchip®ID CORE XT™ test to assess the risk of developing antibodies to non-ABO antigens and ensure compatibility for future transfusions.