How To Use CPT Code 0143U

CPT 0143U describes a specific proprietary laboratory analysis (PLA) test used to screen for the presence of 120 or more drugs or drug metabolites in urine specimens. This article will cover the official description, procedure, qualifying circumstances, appropriate usage, documentation requirements, billing guidelines, historical information, and examples of CPT code 0143U.

1. What is CPT Code 0143U?

CPT 0143U is a unique laboratory test used to analyze urine specimens for the presence of 120 or more drugs or drug metabolites. This test utilizes quantitative liquid chromatography with tandem mass spectrometry (LC-MS/MS) and multiple reaction monitoring (MRM) to accurately identify and quantify the substances in the sample. It provides a comprehensive report on possible drug reactions, descriptions of the drugs and breakdown products, and sample validation.

2. Official Description

The official description of CPT code 0143U is: ‘Drug assay, definitive, 120 or more drugs or metabolites, urine, quantitative liquid chromatography with tandem mass spectrometry (LC-MS/MS) using multiple reaction monitoring (MRM), with drug or metabolite description, comments including sample validation, per date of service.’

3. Procedure

1. The laboratory receives a urine specimen for analysis.
2. The specimen undergoes quantitative liquid chromatography with tandem mass spectrometry (LC-MS/MS) using multiple reaction monitoring (MRM) to separate and identify the drugs or drug metabolites present.
3. The laboratory performs sample validation, ensuring the authenticity of the specimen by comparing it to buccal cells from a cheek swab or other methods.
4. The results are analyzed, and a comprehensive report is generated, including descriptions of the drugs and breakdown products detected, possible drug reactions, and any relevant comments.

4. Qualifying circumstances

CPT 0143U is used when there is a need to screen for the presence of 120 or more drugs or drug metabolites in urine specimens. This test is often ordered by clinicians to screen for illicit drug use, monitor medication compliance, and evaluate the presence of various drugs, over-the-counter ingredients, and metabolites. It is important to note that this code is specific to the CareViewRx® test from Newstar Medical Laboratories LLC.

5. When to use CPT code 0143U

CPT code 0143U should be used when there is a need to perform a definitive urine drug screen using LC-MS/MS to identify 120 or more drugs or drug metabolites. It is important to ensure that the test being performed is the specific proprietary test associated with this code, as other drug assays may have different codes. This code should only be reported for a single specimen analyzed on a single date of service.

6. Documentation requirements

To support a claim for CPT code 0143U, the documentation should include:

• Reason for ordering the test and the clinical indication
• Details of the specific drugs or drug metabolites being tested for
• Date of service and the specific specimen analyzed
• Results of the analysis, including descriptions of the drugs and breakdown products detected
• Any relevant comments or observations

7. Billing guidelines

When billing for CPT code 0143U, it is important to ensure that the test being performed is the specific proprietary test associated with this code. This code should not be reported with any other CPT code. It is also advisable to check with the appropriate payer regarding payment for specimen collection, as some payers may reimburse separately for this service.

8. Historical information

CPT code 0143U was added to the Current Procedural Terminology system on January 1, 2020. There have been no updates or changes to the code since its addition.

9. Examples

1. A clinician orders CPT code 0143U to screen a urine specimen for the presence of 120 or more drugs in a patient with a history of substance abuse.
2. A pain management specialist utilizes CPT code 0143U to monitor a patient’s compliance with prescribed medications and to detect the presence of any illicit drugs.
3. A forensic toxicologist performs CPT code 0143U to analyze a urine sample as part of a criminal investigation.
4. A rehabilitation center uses CPT code 0143U to evaluate a patient’s drug use history and to guide their treatment plan.
5. A workplace drug testing program employs CPT code 0143U to ensure the safety and integrity of their workforce.
6. A healthcare provider orders CPT code 0143U to assess a patient’s medication adherence and to detect any potential drug interactions.
7. A pain management clinic utilizes CPT code 0143U to monitor a patient’s opioid use and to detect the presence of any illicit substances.
8. A physician orders CPT code 0143U to evaluate a patient’s compliance with prescribed medications and to detect any unauthorized drug use.
9. A substance abuse treatment facility employs CPT code 0143U to assess a patient’s progress in their recovery journey and to detect any potential relapses.
10. A healthcare provider uses CPT code 0143U to evaluate a patient’s medication regimen and to ensure that they are receiving the appropriate treatment.