How To Use CPT Code 38210

CPT 38210 describes the preparation of hematopoietic progenitor cells for transplant by reducing the number of T cells in the solution. This article will cover the description, procedure, qualifying circumstances, appropriate usage, documentation requirements, billing guidelines, historical information and billing examples.

1. What is CPT Code 38210?

CPT 38210 can be used to describe the preparation of hematopoietic progenitor cells for transplant by specifically depleting T cells within the harvested cells. This code is used when the provider modifies the solution to minimize the chances of rejection by reducing the number of T cells present.

2. Official Description

The official description of CPT code 38210 is: ‘Transplant preparation of hematopoietic progenitor cells; specific cell depletion within harvest, T-cell depletion.’

3. Procedure

1. The provider harvests the hematopoietic progenitor cells (HPCs) and preserves them.
2. The cells are thawed and prepared for transplant.
3. The provider uses various techniques, such as elutriation, agglutination, or CD34-positive cell enrichment, to specifically deplete T cells within the harvested cells.
4. The solution is then ready for transplant in a patient with a higher risk of rejection.

4. Qualifying circumstances

CPT 38210 is used when the provider prepares the hematopoietic progenitor cells for transplant by specifically depleting T cells within the harvested cells. This procedure is performed to minimize the chances of rejection in patients who are at a greater risk of graft rejection. T cells are primarily responsible for the rejection of a graft from another person. The provider may use techniques such as elutriation, agglutination, or CD34-positive cell enrichment to remove unwanted T cells from the transplant preparation.

5. When to use CPT code 38210

CPT code 38210 should be used when the provider performs the specific cell depletion of T cells within the harvested hematopoietic progenitor cells. This code is appropriate when the provider modifies the solution to minimize the chances of rejection in patients who are at a higher risk of graft rejection.

6. Documentation requirements

To support a claim for CPT 38210, the provider must document the following information:

• Reason for performing the specific cell depletion within the harvested cells
• Techniques used for depleting T cells, such as elutriation, agglutination, or CD34-positive cell enrichment
• Date and time of the procedure
• Details of the solution preparation
• Any additional relevant information or findings
• Provider’s signature

7. Billing guidelines

When billing for CPT 38210, ensure that the provider performs the specific cell depletion of T cells within the harvested hematopoietic progenitor cells. This code should be reported only once per day. It is important to note that CPT code 38210 should not be reported if CPT codes 38204 to 38232 have already been performed in the previous seven days. Additionally, consider the location of the testing when coding these procedures.

8. Historical information

CPT 38210 was added to the Current Procedural Terminology system on January 1, 2003. There have been no updates to the code since its addition.

9. Examples

1. A provider performing specific cell depletion of T cells within harvested hematopoietic progenitor cells for a patient with a high risk of graft rejection.
2. A provider using the CD34-positive cell enrichment technique to remove T cells from the transplant preparation for a patient undergoing hematopoietic progenitor cell transplant.
3. A provider performing agglutination to deplete T cells within the harvested cells for a patient receiving hematopoietic progenitor cell transplant.
4. A provider utilizing elutriation to specifically deplete T cells within the harvested hematopoietic progenitor cells for a patient at a higher risk of graft rejection.
5. A provider preparing the hematopoietic progenitor cells for transplant by reducing the number of T cells using various techniques such as elutriation, agglutination, or CD34-positive cell enrichment.
6. A provider performing specific cell depletion of T cells within the harvested hematopoietic progenitor cells to minimize the chances of graft rejection in a patient.
7. A provider using the CD34-positive cell enrichment technique to remove T cells from the transplant preparation for a patient with a higher risk of graft rejection.
8. A provider performing agglutination to deplete T cells within the harvested cells for a patient undergoing hematopoietic progenitor cell transplant.
9. A provider utilizing elutriation to specifically deplete T cells within the harvested hematopoietic progenitor cells for a patient at a greater risk of graft rejection.
10. A provider preparing the hematopoietic progenitor cells for transplant by reducing the number of T cells using various techniques such as elutriation, agglutination, or CD34-positive cell enrichment.