How To Use CPT Code 81175

CPT 81175 describes the analysis of the full gene sequence for the ASXL1 (additional sex combs like 1, transcriptional regulator) gene. This article will cover the description, procedure, qualifying circumstances, appropriate usage, documentation requirements, billing guidelines, historical information, similar codes and billing examples.

1. What is CPT Code 81175?

CPT 81175 can be used to describe the analysis of the entire gene sequence for the ASXL1 gene. This code is used when a lab analyst performs the technical steps involved in analyzing the gene, from extracting nucleic acids to detecting the target genes using a specimen such as blood. The analysis of the ASXL1 gene can help with the diagnosis and prognosis of conditions such as myeloproliferative neoplasms, myelodysplastic syndromes, and chronic myelomonocytic leukemia.

2. Official Description

The official description of CPT code 81175 is: ‘ASXL1 (additional sex combs like 1, transcriptional regulator) (eg, myelodysplastic syndrome, myeloproliferative neoplasms, chronic myelomonocytic leukemia), gene analysis; full gene sequence.’

3. Procedure

1. The lab analyst performs the technical steps involved in analyzing the full gene sequence of the ASXL1 gene.
2. This includes extracting nucleic acids, increasing and stabilizing the quantity of nucleic acid for analysis, and detecting the target genes using methods such as nucleic acid probes.
3. A specimen, such as blood, is used for the analysis.

4. Qualifying circumstances

CPT 81175 is commonly ordered by clinicians to help with the diagnosis and prognosis of patients with conditions such as myeloproliferative neoplasms, myelodysplastic syndromes, and chronic myelomonocytic leukemia. The analysis of the ASXL1 gene can provide valuable information in these cases.

5. When to use CPT code 81175

CPT code 81175 should be used when a lab analyst performs the analysis of the full gene sequence for the ASXL1 gene. It is appropriate to use this code when the analysis is ordered by a clinician to aid in the diagnosis and prognosis of conditions related to the ASXL1 gene.

6. Documentation requirements

To support a claim for CPT 81175, documentation should include:

• Order for the analysis of the ASXL1 gene
• Details of the technical steps performed by the lab analyst
• Specimen used for the analysis
• Results of the analysis

7. Billing guidelines

When billing for CPT 81175, ensure that the analysis of the full gene sequence for the ASXL1 gene is performed by a lab analyst. It is important to follow the specific guidelines provided by payers regarding the billing of this code. Additionally, be aware of any other codes that may need to be reported in conjunction with CPT 81175.

8. Historical information

CPT 81175 was added to the Current Procedural Terminology system on January 1, 2018. There have been no updates to the code since its addition.

9. Examples

1. A lab analyst performs the analysis of the full gene sequence for the ASXL1 gene to aid in the diagnosis and prognosis of a patient with myeloproliferative neoplasms.
2. The ASXL1 gene is analyzed by a lab analyst to provide valuable information for the management of a patient with myelodysplastic syndromes.
3. A clinician orders the analysis of the full gene sequence for the ASXL1 gene to assist in the diagnosis and prognosis of a patient with chronic myelomonocytic leukemia.
4. The ASXL1 gene is analyzed by a lab analyst to help determine the appropriate treatment plan for a patient with myeloproliferative neoplasms.
5. A lab analyst performs the analysis of the full gene sequence for the ASXL1 gene to aid in the monitoring of disease progression in a patient with myelodysplastic syndromes.
6. The ASXL1 gene is analyzed by a lab analyst to provide information on the prognosis of a patient with chronic myelomonocytic leukemia.
7. A clinician orders the analysis of the full gene sequence for the ASXL1 gene to assist in the identification of potential therapeutic targets for a patient with myeloproliferative neoplasms.
8. The ASXL1 gene is analyzed by a lab analyst to help guide the selection of appropriate treatment options for a patient with myelodysplastic syndromes.
9. A lab analyst performs the analysis of the full gene sequence for the ASXL1 gene to aid in the assessment of disease progression in a patient with chronic myelomonocytic leukemia.
10. The ASXL1 gene is analyzed by a lab analyst to provide information on the response to treatment in a patient with myeloproliferative neoplasms.