How To Use CPT Code 86362

CPT 86362 describes a specific test used to identify an antibody called myelin oligodendrocyte glycoprotein (MOG-IgG1) in a patient’s serum specimen. This article will cover the official description, procedure, qualifying circumstances, appropriate usage, documentation requirements, billing guidelines, historical information, similar codes and billing examples.

1. What is CPT Code 86362?

CPT 86362 can be used to identify the presence of an antibody called myelin oligodendrocyte glycoprotein (MOG-IgG1) in a patient’s serum specimen. This test is typically performed using a cell-based immunofluorescence assay (CBA) method. Clinicians may order this test to help distinguish neuromyelitis optica (NMO) from a similar condition known as MOG-encephalomyelitis (MOG-EM) after a negative aquaporin-4 antibody test.

2. Official Description

The official description of CPT code 86362 is: ‘Myelin oligodendrocyte glycoprotein (MOG-IgG1) antibody; cell-based immunofluorescence assay (CBA), each.’

3. Procedure

1. The lab analyst performs a cell-based immunofluorescence assay (CBA) to detect the presence of MOG-IgG1 antibody in the patient’s serum specimen.
2. The CBA method involves incubating a human-tissue cell-culture line with MOG antigens, fluorescent stain, and the patient’s specimen.
3. After incubation, the specimen is analyzed using fluorescence microscopy to identify the presence of MOG-IgG1 antibody.

4. Qualifying circumstances

CPT 86362 is used when clinicians suspect the presence of MOG-IgG1 antibody in a patient’s serum specimen. This test is typically ordered after a negative aquaporin-4 antibody test to help distinguish between neuromyelitis optica (NMO) and MOG-encephalomyelitis (MOG-EM). The test is performed on serum specimens and requires the use of a cell-based immunofluorescence assay (CBA) method.

5. When to use CPT code 86362

CPT code 86362 should be used when clinicians want to identify the presence of MOG-IgG1 antibody in a patient’s serum specimen. This test is specifically used to distinguish between neuromyelitis optica (NMO) and MOG-encephalomyelitis (MOG-EM) after a negative aquaporin-4 antibody test. It is important to use this code when the test is performed using a cell-based immunofluorescence assay (CBA) method.

6. Documentation requirements

To support a claim for CPT code 86362, the following documentation is required:

• Indication for the test, such as suspicion of MOG-EM after a negative aquaporin-4 antibody test
• Method used for the test, specifically mentioning the cell-based immunofluorescence assay (CBA)
• Date of the test
• Results of the test, indicating the presence or absence of MOG-IgG1 antibody
• Signature of the lab analyst performing the test

7. Billing guidelines

When billing for CPT code 86362, ensure that the test is performed using a cell-based immunofluorescence assay (CBA) method. It is important to select the correct code for MOG-IgG1 antibody detection and not use a less-specific code. Some payers may also separately reimburse for specimen collection. If the test result is positive, the lab may perform an additional separately billable test called a titer to determine the level of the antibody in the specimen.

8. Historical information

CPT code 86362 was added to the Current Procedural Terminology system on January 1, 2022. There have been no updates or changes to the code since its addition.

9. Examples

1. A clinician orders CPT code 86362 to detect the presence of MOG-IgG1 antibody in a patient’s serum specimen after a negative aquaporin-4 antibody test.
2. After suspecting MOG-EM in a patient, a clinician requests CPT code 86362 to confirm the presence of MOG-IgG1 antibody using a cell-based immunofluorescence assay (CBA).
3. A patient with symptoms resembling NMO undergoes CPT code 86362 to differentiate between NMO and MOG-EM based on the presence of MOG-IgG1 antibody.
4. Following a negative aquaporin-4 antibody test, a clinician orders CPT code 86362 to determine if MOG-IgG1 antibody is present in a patient’s serum specimen.
5. A patient with suspected MOG-EM undergoes CPT code 86362 to confirm the presence of MOG-IgG1 antibody using a cell-based immunofluorescence assay (CBA) method.
6. After ruling out other conditions, a clinician orders CPT code 86362 to detect the presence of MOG-IgG1 antibody in a patient’s serum specimen.
7. A patient with symptoms suggestive of MOG-EM undergoes CPT code 86362 to confirm the presence of MOG-IgG1 antibody.
8. Following a negative aquaporin-4 antibody test, a clinician orders CPT code 86362 to determine if MOG-IgG1 antibody is present in a patient’s serum specimen.