How To Use CPT Code 89325

CPT 89325 describes the laboratory procedure used to measure sperm antibodies in samples such as male semen or female serum. This article will cover the description, procedure, qualifying circumstances, appropriate usage, documentation requirements, billing guidelines, historical information, similar codes and billing examples.

1. What is CPT Code 89325?

CPT 89325 can be used to describe the laboratory procedure performed to measure sperm antibodies in samples, such as male semen or female serum. This code is used when a lab analyst mixes the sample with specific substances to determine the presence and quantity of sperm antibodies. The test may use methods like immunoassay, where the antibodies react with reagent antigens to measure their amount.

2. Official Description

The official description of CPT code 89325 is: ‘Measurement of sperm antibodies, direct immunobead binding, each serum or semen specimen.’

3. Procedure

1. The lab analyst receives a sample, either male semen or female serum, to measure the presence of sperm antibodies.
2. The analyst mixes the sample with specific substances, such as immunobeads, to facilitate the binding of sperm antibodies.
3. Using a microscope, the analyst counts 100 cells or more to determine the proportion with binding of the bead to the sperm, indicating the presence of antibodies.
4. The analyst records the results and prepares a report for the clinician.

4. Qualifying circumstances

CPT 89325 is used when there is a need to diagnose infertility problems related to the presence of sperm antibodies. Males may produce these antibodies in semen due to factors like injury, surgery (e.g., vasectomy), or infection, which can inhibit the sperm’s ability to fertilize an egg. Females may also produce serum antibodies to sperm, although this is a rare occurrence with an unknown cause. Clinicians typically order this procedure in specialized facilities that focus on reproductive medicine and infertility treatments.

5. When to use CPT code 89325

CPT code 89325 should be used when a lab analyst performs the measurement of sperm antibodies in samples of male semen or female serum. It is appropriate when there is a clinical suspicion of infertility problems related to the presence of these antibodies. This code should not be used for other purposes or in the absence of specific indications.

6. Documentation requirements

To support a claim for CPT 89325, the documentation should include:

• Indication for the test and the reason for suspecting the presence of sperm antibodies
• Type of sample used (male semen or female serum)
• Details of the specific substances or reagents used in the test
• Date and time of the procedure
• Results of the test, including the proportion of sperm cells with binding of immunobeads
• Signature of the lab analyst performing the procedure

7. Billing guidelines

When billing for CPT 89325, ensure that the procedure is performed by a qualified lab analyst and that the appropriate sample (male semen or female serum) is used. There are no specific guidelines regarding reporting this code with other codes. However, it is important to follow the standard billing practices and guidelines set by the payer.

8. Historical information

CPT 89325 was added to the Current Procedural Terminology system on January 1, 1990. There have been no updates or changes to the code since its addition.

9. Examples

1. A lab analyst performing the measurement of sperm antibodies in a sample of male semen to investigate infertility issues.
2. A clinician ordering the measurement of sperm antibodies in a sample of female serum to assess potential causes of infertility.
3. A lab technician conducting the procedure to measure sperm antibodies in a sample of male semen after a patient’s vasectomy to determine if the procedure was successful.
4. A reproductive medicine specialist requesting the measurement of sperm antibodies in a sample of female serum to investigate unexplained infertility.
5. A lab analyst performing the measurement of sperm antibodies in a sample of male semen to assess the impact of a previous injury on fertility.
6. A clinician ordering the measurement of sperm antibodies in a sample of female serum to evaluate potential causes of recurrent miscarriages.
7. A lab technician conducting the procedure to measure sperm antibodies in a sample of male semen to assess the effectiveness of a specific treatment for infertility.
8. A reproductive medicine specialist requesting the measurement of sperm antibodies in a sample of female serum to investigate suspected immune-related infertility issues.
9. A lab analyst performing the measurement of sperm antibodies in a sample of male semen to determine the presence of antibodies that may affect fertility.
10. A clinician ordering the measurement of sperm antibodies in a sample of female serum to assess potential causes of failed in vitro fertilization (IVF) attempts.