cpt 91313, cpt code 91313, 91313 cpt code

CPT 91313 | COVID-19 Vaccine: mRNA-LNP, Intramuscular, 50 mcg/0.5 mL

CPT code 91313 describes a vaccine that reduces the risk of COVID-19, using mRNA-LNP technology and administered intramuscularly in a 50 mcg/0.5 mL dosage.

What Is CPT Code 91313?

CPT 91313 describes a vaccine designed to reduce the risk of contracting COVID-19, the disease caused by the SARS-CoV-2 virus.

The vaccine is mRNA-LNP, which means it uses messenger ribonucleic acid (mRNA) to instruct the patient’s cells to produce spike proteins that the coronavirus uses to bind to host cells.

The vaccine is bivalent, meaning it contains mRNA components for both the original strain and the omicron variant of the virus.

Lipid nanoparticles (LNPs) are used as a delivery system for the vaccine, which has a dosage of 50 mcg/0.5 mL and is administered intramuscularly (into the muscle). The provider separately reports the administration of the vaccine, which is preservative-free.


The CPT book describes CPT code 91313 as: “Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (coronavirus disease [COVID-19]) vaccine, mRNA-LNP, spike protein, bivalent, preservative-free, 50 mcg/0.5 mL dosage, for intramuscular use.”


This code represents a SARS–CoV–2 vaccine product administered to reduce the patient’s risk of contracting COVID–19.

The vaccine is preservative-free. This is an mRNA–LNP vaccine. Messenger ribonucleic acid (mRNA) carries genetic information instructing the patient’s cells to make the spike proteins that the coronavirus uses to bind to a host cell.

As a bivalent vaccine, the booster contains mRNA components of both the original strain and the omicron variant.

Once the patient’s cells produce the spike proteins, they trigger an immune response that helps protect the patient from getting COVID–19. Lipid nanoparticles (LNPs) are tiny particles that act as the delivery system for the vaccine.

How To Use CPT 91313

The dosage is 50 mcg/0.5 mL. The provider performs separately reportable administration of the SARS–CoV–2 vaccine. The route is intramuscular, meaning into the muscle.

CPT 91313 represents the vaccine product. You may use CPT code 91313 for the Moderna COVID–19 bivalent vaccine with a 50 mcg/0.5 mL dosage.  

Select booster code CPT 0134A for administration.

Check the patient’s age and service date for CPT code 91313. Different effective dates apply based on the patient’s age, and you cannot bill 91313 before the effective date for your patient’s age.

Do not bill CPT 91313 with administration codes CPT 0011A, CPT 0012A, CPT 0013A, CPT 0064A, CPT 0091A, CPT 0092A, CPT 0093A, CPT 0094A, CPT 0111A, CPT CPT 0112A, CPT 0113A, CPT 0144A, or CPT 0164A.

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