How To Use CPT Code 0025U

CPT 0025U describes a specific lab test called the tenofovir quantitation test on urine. This article will cover the official description, procedure, qualifying circumstances, appropriate usage, documentation requirements, billing guidelines, historical information, and examples of CPT code 0025U.

1. What is CPT Code 0025U?

CPT 0025U can be used to describe the tenofovir quantitation test on urine. This test is performed using liquid chromatography with tandem mass spectrometry (LC-MS/MS) to measure the specific quantity of tenofovir in the urine. It is often ordered by clinicians to determine whether patients with chronic hepatitis B or HIV/AIDS are receiving the optimal dosage of tenofovir.

2. Official Description

The official description of CPT code 0025U is: ‘Tenofovir, by liquid chromatography with tandem mass spectrometry (LC-MS/MS), urine, quantitative.’

3. Procedure

  1. The lab analyst performs a quantitative drug test on the urine sample using liquid chromatography with tandem mass spectrometry (LC-MS/MS).
  2. The test separates the components of the urine sample by passing it through a mobile phase in which the components move at different rates.
  3. The mass spectrometry technique is then used to identify and quantify the components of the urine sample.
  4. The specific quantity of tenofovir in the urine is measured.

4. Qualifying circumstances

The tenofovir quantitation test on urine is typically ordered for patients with chronic hepatitis B or HIV/AIDS to determine the effectiveness of their treatment. It is important to note that CPT code 0025U is a proprietary laboratory analyses (PLA) code, meaning it describes a unique lab test performed by a specific lab or manufacturer.

5. When to use CPT code 0025U

CPT code 0025U should be used when the tenofovir quantitation test on urine is performed using liquid chromatography with tandem mass spectrometry (LC-MS/MS) to measure the specific quantity of tenofovir. It is important to use this code only for the described test and not report it with any other CPT code.

6. Documentation requirements

To support a claim for CPT code 0025U, the documentation should include:

  • Indication for the test, such as chronic hepatitis B or HIV/AIDS
  • Specific details of the test performed, including the use of liquid chromatography with tandem mass spectrometry (LC-MS/MS)
  • Date of service
  • Results of the test, including the specific quantity of tenofovir measured

7. Billing guidelines

When billing for CPT code 0025U, ensure that the test is performed by the appropriate lab or manufacturer. Report one unit of this code for a single specimen analyzed on a single date of service. It is important to check with the appropriate payer regarding payment for specimen collection. Do not report this test with any other CPT code.

8. Historical information

CPT code 0025U was added to the Current Procedural Terminology system on January 1, 2018. There have been no updates to the code since its addition.

9. Examples

  1. A lab performing the tenofovir quantitation test on urine using liquid chromatography with tandem mass spectrometry (LC-MS/MS) to measure the specific quantity of tenofovir for a patient with chronic hepatitis B.
  2. A clinician ordering the tenofovir quantitation test on urine to assess the effectiveness of tenofovir treatment for a patient with HIV/AIDS.
  3. A lab technician analyzing a urine sample using liquid chromatography with tandem mass spectrometry (LC-MS/MS) to determine the concentration of tenofovir for a patient with chronic hepatitis B.
  4. A physician requesting the tenofovir quantitation test on urine to monitor the dosage of tenofovir for a patient with HIV/AIDS.
  5. A lab performing the tenofovir quantitation test on urine using liquid chromatography with tandem mass spectrometry (LC-MS/MS) to measure the specific quantity of tenofovir for a patient with chronic hepatitis B and HIV/AIDS.
  6. A clinician ordering the tenofovir quantitation test on urine to assess the effectiveness of tenofovir treatment for a patient with chronic hepatitis B and HIV/AIDS.
  7. A lab technician analyzing a urine sample using liquid chromatography with tandem mass spectrometry (LC-MS/MS) to determine the concentration of tenofovir for a patient with chronic hepatitis B and HIV/AIDS.
  8. A physician requesting the tenofovir quantitation test on urine to monitor the dosage of tenofovir for a patient with chronic hepatitis B and HIV/AIDS.
  9. A lab performing the tenofovir quantitation test on urine using liquid chromatography with tandem mass spectrometry (LC-MS/MS) to measure the specific quantity of tenofovir for a patient with chronic hepatitis B and co-infection of HIV.
  10. A clinician ordering the tenofovir quantitation test on urine to assess the effectiveness of tenofovir treatment for a patient with chronic hepatitis B and co-infection of HIV.

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