How To Use CPT Code 80339

CPT 80339 describes the measurement or detection of one to three antiepileptic drugs in a patient specimen. This article will cover the description, procedure, qualifying circumstances, appropriate usage, documentation requirements, billing guidelines, historical information, similar codes and billing examples.

1. What is CPT Code 80339?

CPT 80339 can be used to describe the measurement or detection of one to three antiepileptic drugs in a patient specimen. This code is used when a lab analyst performs a test to determine the presence or amount of these drugs in a specimen, such as urine or serum. The specific antiepileptic drugs being tested for are not specified in other CPT codes.

2. Official Description

The official description of CPT code 80339 is: ‘Antiepileptics, not otherwise specified; 1-3.’

3. Procedure

1. The lab analyst receives a patient specimen, such as urine or serum, for testing.
2. The analyst selects a methodology, such as high performance liquid chromatography (HPLC), to measure or detect the presence of one to three antiepileptic drugs in the specimen.
3. The specimen is prepared and analyzed using the chosen methodology.
4. The lab analyst quantitates the amount of antiepileptic drugs present in the specimen or determines if the specimen is positive or negative for the drugs.
5. The results of the analysis are documented and reported to the healthcare provider.

4. Qualifying circumstances

CPT 80339 is used when a healthcare provider orders a test to measure or detect the presence of one to three antiepileptic drugs in a patient specimen. This test may be ordered to diagnose an overdose of anticonvulsant medication or to assess patient compliance with a prescribed regimen. The specific antiepileptic drugs being tested for are not specified in other CPT codes.

5. When to use CPT code 80339

CPT code 80339 should be used when a lab analyst performs a test to measure or detect the presence of one to three antiepileptic drugs in a patient specimen. This code is not appropriate for testing for four or more antiepileptic drugs. If the test involves four to six drugs, use CPT code 80340. If the test involves seven or more drugs, use CPT code 80341.

6. Documentation requirements

To support a claim for CPT code 80339, the healthcare provider must document the following information:

• Reason for ordering the test, such as suspected overdose or assessment of patient compliance
• Type of specimen tested, such as urine or serum
• Methodology used for analysis, such as high performance liquid chromatography (HPLC)
• Results of the analysis, including the presence or amount of antiepileptic drugs in the specimen
• Signature of the lab analyst performing the test

7. Billing guidelines

When billing for CPT code 80339, ensure that the test is performed by a lab analyst and that it involves the measurement or detection of one to three antiepileptic drugs in a patient specimen. Do not report CPT code 80339 if the test involves four or more drugs. Consider using modifier 26 for professional component billing and modifier TC for technical component billing, if applicable.

8. Historical information

CPT code 80339 was added to the Current Procedural Terminology system on January 1, 2015. There have been no updates to the code since its addition.

9. Examples

1. A lab analyst measures the amount of carbamazepine, phenytoin, and valproic acid in a patient’s urine specimen using high performance liquid chromatography (HPLC).
2. A healthcare provider orders a test to detect the presence of lamotrigine in a patient’s serum specimen to assess compliance with a prescribed regimen.
3. A lab analyst quantitates the amount of levetiracetam in a patient’s urine specimen using a definitive drug testing methodology.
4. A healthcare provider suspects an overdose of topiramate and orders a test to measure its presence in a patient’s serum specimen.
5. A lab analyst performs a test to detect the presence of oxcarbazepine, zonisamide, and ethosuximide in a patient’s urine specimen using a specific analytical technique.
6. A healthcare provider orders a test to measure the amount of gabapentin in a patient’s serum specimen to determine the effectiveness of the prescribed dosage.
7. A lab analyst detects the presence of pregabalin in a patient’s urine specimen using a sensitive analytical method.
8. A healthcare provider suspects non-compliance with a prescribed regimen of phenobarbital and orders a test to measure its presence in a patient’s serum specimen.
9. A lab analyst measures the amount of tiagabine and vigabatrin in a patient’s urine specimen using a validated analytical procedure.
10. A healthcare provider orders a test to detect the presence of primidone in a patient’s serum specimen to confirm adherence to the prescribed treatment plan.